Characterizing the Intraoperative Microelectrode Recording-Induced Microlesion Effect on Motor Symptoms in Patients with Parkinson's Disease Undergoing Deep Brain Stimulation of the Subthalamic Nucleus

Dursun Aygun, Umit Akin Dere*, Onur Yildiz, Yasin Temel, Ersoy Kocabicak

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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AIM: To investigate microelectrode recording (MER)-induced microlesion effect (MLE) on the motor symptoms of 30 patients with Parkinson's disease (PD) who underwent deep brain stimulation of the subthalamic nucleus.

MATERIAL and METHODS: MER-induced MLE was evaluated based on the difference between tremor, rigidity, and bradykinesia scores in the preoperative off-state and intraoperative state following MER and before test stimulation.

RESULTS: MLE scores improved by 21.7% [left (L) side] and by 13.6% [right (R) side] from baseline (p 0.05).

CONCLUSION: MER-induced MLE improved motor symptoms and was not correlated with the number of microelectrodes used during the procedure.

Original languageEnglish
Pages (from-to)430-433
Number of pages4
JournalTurkish Neurosurgery
Issue number3
Publication statusPublished - 2019


  • Parkinson's disease
  • Subthalamic nucleus
  • Deep brain stimulation
  • Microelectrode recording
  • Microlesion effect

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