Characterization of nonresponse to high caloric oral nutritional therapy in depleted patients with chronic obstructive pulmonary disease

E.C. Creutzberg, A.M.W.J. Schols, C.A.P.M. Weling-Scheepers, W.A. Buurman, E.F.M. Wouters

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Nutritional support can increase body weight and physiologic function in COPD, but there are some patients who do not respond to nutritional therapy. The aim of this prospective study was to describe the nonresponse to 8 wk of oral nutritional supplementation therapy (500 to 750 kcal/d extra), implemented in an inpatient pulmonary rehabilitation program, with respect to lung function, body composition, energy balance, and systemic inflammatory profile in 24 (16 male) depleted patients with COPD. On the basis of the weight change after 8 wk, patients were divided into three groups (Group 1: weight gain ratio.
Original languageEnglish
Pages (from-to)745-752
Number of pages8
JournalAmerican Journal of Respiratory and Critical Care Medicine
Issue number3 (Pt 1)
Publication statusPublished - 1 Jan 2000

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