TY - JOUR
T1 - Characteristics of participants who benefit most from personalised nutrition
T2 - findings from the pan-European Food4Me randomised controlled trial
AU - Livingstone, Katherine M.
AU - Celis-Morales, Carlos
AU - Navas-Carretero, Santiago
AU - San-Cristobal, Rodrigo
AU - Forster, Hannah
AU - Woolhead, Clara
AU - O'Donovan, Clare B.
AU - Moschonis, George
AU - Manios, Yannis
AU - Traczyk, Iwona
AU - Gundersen, Thomas E.
AU - Drevon, Christian A.
AU - Marsaux, Cyril F. M.
AU - Fallaize, Rosalind
AU - Macready, Anna L.
AU - Daniel, Hannelore
AU - Saris, Wim H. M.
AU - Lovegrove, Julie A.
AU - Gibney, Mike
AU - Gibney, Eileen R.
AU - Walsh, Marianne
AU - Brennan, Lorraine
AU - Martinez, J. A.
AU - Mathers, John C.
AU - Food4Me Study
N1 - Funding Information:
This work was supported by the European Commission under the Food, Agriculture, Fisheries and Biotechnology Theme of the Seventh Framework Programme for Research and Technological Development (265494). The sponsor had no role in the study design or conduct, data collection, management, analysis or interpretation, manuscript preparation, review or approval.
Funding Information:
T. E. G. is the CEO of Vitas Ltd. T. E. G. and C. A. D. have shares in Vitas Ltd, and C. A. D. is a board member and consultant in Vitas Ltd; no other conflict of interests. K. M. L. is a consultant for HeadUpLabs. WHMS has received research support from several food companies such as Nestle, DSM, Unilever, Nutrition et Sante and Danone as well as pharmaceutical companies such as GSK, Novartis and Novo Nordisk. He is a medical consultant for N&S and is an unpaid scientific adviser for the International Life Science Institute, ILSI Europe. M. G. reports that he is a non-remunerated member of the Google Food Innovation Lab Community of Practice on Personalized Nutrition. J. C. M. reports grants from European Union, during the conduct of the study; grants and personal fees from Medical Research Council, grants and personal fees from Biotechnology and Biological Sciences Research Council, personal fees and non-financial support from Waltham Pet Nutrition, personal fees and non-financial support from University of Wageningen, the Netherlands, non-financial support from Technical University Munich, non-financial support from University College Dublin, non-financial support from University of Groningen, the Netherlands, non-financial support from University of Maastricht, the Netherlands, outside the submitted work. J. A. L. has received research funding outside of the submitted work from Medical Research Council, Biotechnology and Biological Sciences Research Council and European Union with in kind provision of foods from Arla, AAK and Unilever and research funding from the Dairy Council, UK. She was a member of the UK Governments Scientific Advisor Committee for Nutrition (SACN) and a member of SACN’s Carbohydrate Working Group and Saturated Fats Working Group during and after the study.
Funding Information:
This work was supported by the European Commission under the Food, Agriculture, Fisheries and Biotechnology Theme of the Seventh Framework Programme for Research and Technological Development (265494). The sponsor had no role in the study design or conduct, data collection, management, analysis or interpretation, manuscript preparation, review or approval.
Publisher Copyright:
© The Authors 2020.
PY - 2020/6/28
Y1 - 2020/6/28
N2 - Little is known about who would benefit from Internet-based personalised nutrition (PN) interventions. This study aimed to evaluate the characteristics of participants who achieved greatest improvements (i.e. benefit) in diet, adiposity and biomarkers following an Internet-based PN intervention. Adults (n 1607) from seven European countries were recruited into a 6-month, randomised controlled trial (Food4Me) and randomised to receive conventional dietary advice (control) or PN advice. Information on dietary intake, adiposity, physical activity (PA), blood biomarkers and participant characteristics was collected at baseline and month 6. Benefit from the intervention was defined as >= 5 % change in the primary outcome (Healthy Eating Index) and secondary outcomes (waist circumference and BMI, PA, sedentary time and plasma concentrations of cholesterol, carotenoids and omega-3 index) at month 6. For our primary outcome, benefit from the intervention was greater in older participants, women and participants with lower HEI scores at baseline. Benefit was greater for individuals reporting greater self-efficacy for 'sticking to healthful foods' and who 'felt weird if [they] didn't eat healthily'. Participants benefited more if they reported wanting to improve their health and well-being. The characteristics of individuals benefiting did not differ by other demographic, health-related, anthropometric or genotypic characteristics. Findings were similar for secondary outcomes. These findings have implications for the design of more effective future PN intervention studies and for tailored nutritional advice in public health and clinical settings.
AB - Little is known about who would benefit from Internet-based personalised nutrition (PN) interventions. This study aimed to evaluate the characteristics of participants who achieved greatest improvements (i.e. benefit) in diet, adiposity and biomarkers following an Internet-based PN intervention. Adults (n 1607) from seven European countries were recruited into a 6-month, randomised controlled trial (Food4Me) and randomised to receive conventional dietary advice (control) or PN advice. Information on dietary intake, adiposity, physical activity (PA), blood biomarkers and participant characteristics was collected at baseline and month 6. Benefit from the intervention was defined as >= 5 % change in the primary outcome (Healthy Eating Index) and secondary outcomes (waist circumference and BMI, PA, sedentary time and plasma concentrations of cholesterol, carotenoids and omega-3 index) at month 6. For our primary outcome, benefit from the intervention was greater in older participants, women and participants with lower HEI scores at baseline. Benefit was greater for individuals reporting greater self-efficacy for 'sticking to healthful foods' and who 'felt weird if [they] didn't eat healthily'. Participants benefited more if they reported wanting to improve their health and well-being. The characteristics of individuals benefiting did not differ by other demographic, health-related, anthropometric or genotypic characteristics. Findings were similar for secondary outcomes. These findings have implications for the design of more effective future PN intervention studies and for tailored nutritional advice in public health and clinical settings.
KW - Food4Me
KW - Personalised nutrition
KW - Internet-based interventions
KW - European
KW - Adults
KW - HEALTHY EATING INDEX
KW - MEDITERRANEAN DIET
KW - PHYSICAL-ACTIVITY
KW - WEIGHT-CONTROL
KW - ADULTS
U2 - 10.1017/s0007114520000653
DO - 10.1017/s0007114520000653
M3 - Article
C2 - 32234083
SN - 0007-1145
VL - 123
SP - 1396
EP - 1405
JO - British Journal of Nutrition
JF - British Journal of Nutrition
IS - 12
M1 - 0007114520000653
ER -