Changes in pain-related fear and pain when avoidance behaviour is no longer effective

Christine M van Vliet*, Ann Meulders, Linda M G Vancleef, Elke Meyers, Johan W S Vlaeyen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Avoidance is considered key in the development of chronic pain. However, little is known about how avoidance behaviour subsequently affects pain-related fear and pain. We investigated this using a robotic arm reaching avoidance task to investigate this. In a between-subjects design both Experimental Group (n=30) and Yoked Control Group (n=30) participants perform either of three movement trajectories (T1-T3) to reach a target location. During acquisition, only participants of the Experimental Group could partially or fully avoid a painful electrocutaneous stimulus by choosing the intermediate trajectory (T2; 50% reinforcement) or the longest trajectory (T3; 0% reinforcement) versus the shortest trajectory (T1: 100% reinforcement). After acquisition, contingencies changed (all trajectories 50% reinforced), and the acquired avoidance behaviour no longer effectively prevented pain from occurring. The Yoked Control Group received the same reinforcement schedule as the Experimental Group irrespective of their behaviour. When avoidance behaviour became ineffective for the Experimental Group, pain-related fear increased for the previously safe(r) trajectories (T2 and T3) and remained the same for T1, whereas pain threshold and tolerance declined. For the Yoked Group, pain-related fear increased for all trajectories. The Experimental Group persisted in emitting avoidance behaviour following the contingency change, albeit at a lower frequency than during acquisition. PERSPECTIVE: Results indicate participants become more afraid of and sensitive to pain, when previously acquired avoidance is no longer effective. Also, participants continue to show avoidance behaviour despite it being not adaptive anymore. These findings suggest that ineffective avoidance may play role in the maintenance and development of chronic pain.

Original languageEnglish
Pages (from-to)494-505
Number of pages12
JournalThe Journal of Pain
Volume21
Issue number3-4
Early online date18 Sep 2019
DOIs
Publication statusPublished - 2020

Keywords

  • Avoidance behavior
  • ineffective avoidance behavior
  • pain-related fear
  • pain
  • pain sensitization
  • CHRONIC MUSCULOSKELETAL PAIN
  • EXTINCTION
  • ANXIETY
  • CONSEQUENCES
  • ACQUISITION
  • MODEL

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