CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer’s disease

S.M. Crivelli, Q. Luo, J.A.A. Stevens, C. Giovagnoni, D. van Kruining, G. Bode, S. den Hoedt, B. Hobo, A.L. Scheithauer, J. Walter, M.T. Mulder, C. Exley, M. Mold, M.M. Mielke, H.E. De Vries, K. Wouters, D.L.A. van den Hove, D. Berkes, M.D. Ledesma, J. VerhaagenM. Losen, E. Bieberich, P. Martinez-Martinez

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Web of Science)
Original languageEnglish
Article number45
Number of pages21
JournalAlzheimer's Research & Therapy
Volume13
Issue number1
DOIs
Publication statusPublished - 17 Feb 2021

Keywords

  • 5xfad
  • adeno-associated virus (aav)
  • alzheimer's disease (ad)
  • amyloid-beta plaques
  • ceramide
  • ceramide transporter protein (cert)
  • microglia
  • neuroinflammation
  • sphingomyelin
  • Adeno-associated virus (AAV)
  • 5xFAD
  • Alzheimer's disease (AD)
  • Neuroinflammation
  • Ceramide transporter protein (CERT)
  • Microglia
  • Ceramide
  • Sphingomyelin
  • Amyloid-beta plaques

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