Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

Laurens E. Franssen; Inger S. Nijhof; Suzana Couto; Mark-David Levin; Gerard M. J. Bos; Annemiek Broijl; Saskia K. Klein; Yan Ren; Maria Wang; Harry R. Koene; Andries C. Bloem; Aart Beeker; Laura M. Faber; Ellen van der Spek; Reinier Raymakers; Roos J. Leguit; Pieter Sonneveld; Sonja Zweegman; Henk Lokhorst; Tuna Mutis; Anjan Thakurta; Xiaozhong Qian; Niels W. C. J. van de Donk

doi:10.3324/haematol.2017.186601

Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

Laurens E. Franssen
, Inger S. Nijhof
, Suzana Couto
, Mark-David Levin
, Gerard M. J. Bos
, Annemiek Broijl
, Saskia K. Klein
, Yan Ren
, Maria Wang
, Harry R. Koene
, Andries C. Bloem
, Aart Beeker
, Laura M. Faber
, Ellen van der Spek
, Reinier Raymakers
, Roos J. Leguit
, Pieter Sonneveld
, Sonja Zweegman
, Henk Lokhorst
, Tuna Mutis

Anjan Thakurta, Xiaozhong Qian, Niels W. C. J. van de Donk^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Original language	English
Pages (from-to)	E368-E371
Number of pages	4
Journal	Haematologica-the Hematology Journal
Volume	103
Issue number	8
DOIs	https://doi.org/10.3324/haematol.2017.186601
Publication status	Published - 31 Jul 2018

Keywords

CELLS
POMALIDOMIDE
EXPRESSION

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http://www.haematologica.org/content/early/2018/03/09/haematol.2017.186601.full.pdf

Cite this

Franssen, L. E., Nijhof, I. S., Couto, S., Levin, M.-D., Bos, G. M. J., Broijl, A., Klein, S. K., Ren, Y., Wang, M., Koene, H. R., Bloem, A. C., Beeker, A., Faber, L. M., van der Spek, E., Raymakers, R., Leguit, R. J., Sonneveld, P., Zweegman, S., Lokhorst, H., ... van de Donk, N. W. C. J. (2018). Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients. Haematologica-the Hematology Journal, 103(8), E368-E371. https://doi.org/10.3324/haematol.2017.186601

@article{3f67c74b6efa4f6a8a16dcb26974802a,

title = "Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients",

keywords = "CELLS, POMALIDOMIDE, EXPRESSION",

author = "Franssen, \{Laurens E.\} and Nijhof, \{Inger S.\} and Suzana Couto and Mark-David Levin and Bos, \{Gerard M. J.\} and Annemiek Broijl and Klein, \{Saskia K.\} and Yan Ren and Maria Wang and Koene, \{Harry R.\} and Bloem, \{Andries C.\} and Aart Beeker and Faber, \{Laura M.\} and \{van der Spek\}, Ellen and Reinier Raymakers and Leguit, \{Roos J.\} and Pieter Sonneveld and Sonja Zweegman and Henk Lokhorst and Tuna Mutis and Anjan Thakurta and Xiaozhong Qian and \{van de Donk\}, \{Niels W. C. J.\}",

year = "2018",

month = jul,

day = "31",

doi = "10.3324/haematol.2017.186601",

language = "English",

volume = "103",

pages = "E368--E371",

journal = "Haematologica-the Hematology Journal",

issn = "0390-6078",

publisher = "Ferrata Storti Foundation",

number = "8",

}

Franssen, LE, Nijhof, IS, Couto, S, Levin, M-D, Bos, GMJ, Broijl, A, Klein, SK, Ren, Y, Wang, M, Koene, HR, Bloem, AC, Beeker, A, Faber, LM, van der Spek, E, Raymakers, R, Leguit, RJ, Sonneveld, P, Zweegman, S, Lokhorst, H, Mutis, T, Thakurta, A, Qian, X & van de Donk, NWCJ 2018, 'Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients', Haematologica-the Hematology Journal, vol. 103, no. 8, pp. E368-E371. https://doi.org/10.3324/haematol.2017.186601

TY - JOUR

T1 - Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

AU - Franssen, Laurens E.

AU - Nijhof, Inger S.

AU - Couto, Suzana

AU - Levin, Mark-David

AU - Bos, Gerard M. J.

AU - Broijl, Annemiek

AU - Klein, Saskia K.

AU - Ren, Yan

AU - Wang, Maria

AU - Koene, Harry R.

AU - Bloem, Andries C.

AU - Beeker, Aart

AU - Faber, Laura M.

AU - van der Spek, Ellen

AU - Raymakers, Reinier

AU - Leguit, Roos J.

AU - Sonneveld, Pieter

AU - Zweegman, Sonja

AU - Lokhorst, Henk

AU - Mutis, Tuna

AU - Thakurta, Anjan

AU - Qian, Xiaozhong

AU - van de Donk, Niels W. C. J.

PY - 2018/7/31

Y1 - 2018/7/31

KW - CELLS

KW - POMALIDOMIDE

KW - EXPRESSION

U2 - 10.3324/haematol.2017.186601

DO - 10.3324/haematol.2017.186601

M3 - Comment/Letter to the editor

C2 - 29545338

SN - 0390-6078

VL - 103

SP - E368-E371

JO - Haematologica-the Hematology Journal

JF - Haematologica-the Hematology Journal

IS - 8

ER -