Ceramide analog [18F]F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer’s disease transgenic mice by functioning as a metabolic probe

Simone M. Crivelli, Daan van Kruining, Qian Luo, Jo A. A. Stevens, Caterina Giovagnoni, Andreas Paulus, Matthias Bauwens, Dusan Berkes, Helga E. de Vries, Monique T. Mulder, Jochen Walter, Etienne Waelkens, Rita Derua, Johannes Swinnen, Jonas Dehairs, Felix M. Mottaghy, Mario Losen, Erhard Bieberich, Pilar Martinez-Martinez*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number19354
Number of pages14
JournalScientific Reports
Volume10
Issue number1
DOIs
Publication statusPublished - 9 Nov 2020

Keywords

  • MOUSE MODEL
  • TRAFFICKING
  • ACCUMULATION
  • TRANSPORTER
  • INHIBITOR
  • APOPTOSIS
  • BARRIER
  • PROTEIN
  • DEATH
  • RISK

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