Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation

J. Spaas*, W.M.A. Franssen, C. Keytsman, L. Blancquaert, T. Vanmierlo, J. Bogie, B. Broux, N. Hellings, J. van Horssen, D.K. Posa, D. Hoetker, S.P. Baba, W. Derave, B.O. Eijnde

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number255
Number of pages19
JournalJournal of Neuroinflammation
Volume18
Issue number1
DOIs
Publication statusPublished - 5 Nov 2021

Keywords

  • Acrolein
  • Carnosine
  • Multiple sclerosis
  • Neuroinflammation
  • Oxidative stress
  • Reactive carbonyl
  • HISTIDINE-CONTAINING DIPEPTIDES
  • MULTIPLE-SCLEROSIS
  • PROTEIN CARBONYLATION
  • OXIDATIVE STRESS
  • CELLS
  • CHEMISTRY
  • DAMAGE
  • SUPPLEMENTATION
  • DETOXIFICATION
  • TRANSCRIPTOME

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