TY - JOUR
T1 - Cardiopulmonary Bypass and Cross-Clamping Times in Aortic Valve Replacement Surgery by Ministernotomy with Sutureless Prosthesis Implantation Compared to Conventional Prosthesis
T2 - A Cross-Sectional Study
AU - Perazzo, Álvaro
AU - Mariani, Silvia
AU - Montenegro, Gabriela Lucena
AU - Conci, Luca
AU - Sepúlveda, Diana Patrícia Lamprea
AU - Steffen, Samuel Padovani
AU - Gaiotto, Fabio Antonio
AU - Lorusso, Roberto
AU - Caldas, Silvio
AU - Lins, Esdras Marques
AU - Leal, João Carlos Ferreira
AU - Moraes, Fernando Ribeiro de
PY - 2025/3/18
Y1 - 2025/3/18
N2 - INTRODUCTION: Valve replacement is one of the effective treatments for aortic valve disease. This study aims to compare cardiopulmonary bypass and ischemia times in aortic valve replacement surgeries using stented biological and sutureless prostheses (PERCEVAL®) through a minimally invasive ministernotomy approach. Methods: This single-center cross-sectional study, conducted from February 2015 to February 2021, assessed clinical and epidemiological characteristics in aortic valve replacement patients. It analyzed factors including hospital stay, early outcomes, valve etiology, intraoperative diagnosis, systolic gradients, left ventricular ejection fraction, and left ventricular mass. Two groups were studied: 12 patients with PERCEVAL® prostheses and 81 with conventional bioprostheses. RESULTS: This study included 93 patients (age: 59 ± 16 years), 61.3% were male, and 80.2% had hypertension; dyslipidemias were present in 34.1% and 25.3% were diabetic. Cardiopulmonary bypass and cross-clamping times were 61 minutes and 41 minutes in the conventional bioprostheses group and 59.5 minutes and 39.5 minutes in the PERCEVAL® group (P=0.143 and P=0.058, respectively). Intensive care unit and overall hospital stays were statistically comparable between both groups (P=0.662 and P=0.599, respectively). All participants survived the 30-day postoperative period, with minimal complications, no significant differences in echocardiographic parameters were observed, yet higher values for certain cardiac function indicators were noted in the conventional bioprostheses group. CONCLUSION: The groups with conventional bioprostheses and sutureless prostheses (PERCEVAL®) didn't display significant differences in the analyzed variables for ministernotomy aortic valve replacement surgery. They exhibited similar results in terms of hospital stay duration, 30-day outcomes, and cardiac function values.
AB - INTRODUCTION: Valve replacement is one of the effective treatments for aortic valve disease. This study aims to compare cardiopulmonary bypass and ischemia times in aortic valve replacement surgeries using stented biological and sutureless prostheses (PERCEVAL®) through a minimally invasive ministernotomy approach. Methods: This single-center cross-sectional study, conducted from February 2015 to February 2021, assessed clinical and epidemiological characteristics in aortic valve replacement patients. It analyzed factors including hospital stay, early outcomes, valve etiology, intraoperative diagnosis, systolic gradients, left ventricular ejection fraction, and left ventricular mass. Two groups were studied: 12 patients with PERCEVAL® prostheses and 81 with conventional bioprostheses. RESULTS: This study included 93 patients (age: 59 ± 16 years), 61.3% were male, and 80.2% had hypertension; dyslipidemias were present in 34.1% and 25.3% were diabetic. Cardiopulmonary bypass and cross-clamping times were 61 minutes and 41 minutes in the conventional bioprostheses group and 59.5 minutes and 39.5 minutes in the PERCEVAL® group (P=0.143 and P=0.058, respectively). Intensive care unit and overall hospital stays were statistically comparable between both groups (P=0.662 and P=0.599, respectively). All participants survived the 30-day postoperative period, with minimal complications, no significant differences in echocardiographic parameters were observed, yet higher values for certain cardiac function indicators were noted in the conventional bioprostheses group. CONCLUSION: The groups with conventional bioprostheses and sutureless prostheses (PERCEVAL®) didn't display significant differences in the analyzed variables for ministernotomy aortic valve replacement surgery. They exhibited similar results in terms of hospital stay duration, 30-day outcomes, and cardiac function values.
KW - Adult
KW - Aged
KW - Aortic Valve
KW - Aortic Valve Disease
KW - Aortic Valve/surgery
KW - Bioprosthesis
KW - Cardiopulmonary Bypass
KW - Cardiopulmonary Bypass/methods
KW - Constriction
KW - Cross-Sectional Studies
KW - Female
KW - Heart Valve Prosthesis
KW - Heart Valve Prosthesis Implantation/methods
KW - Humans
KW - Ischemia
KW - Left Ventricular Function
KW - Length of Stay
KW - Male
KW - Middle Aged
KW - Operative Time
KW - Sternotomy/methods
KW - Sutureless Surgical Procedures/methods
KW - Time Factors
KW - Treatment Outcome
U2 - 10.21470/1678-9741-2024-0290
DO - 10.21470/1678-9741-2024-0290
M3 - Article
SN - 0102-7638
VL - 40
JO - Revista Brasileira de Cirurgia Cardiovascular
JF - Revista Brasileira de Cirurgia Cardiovascular
IS - 2
M1 - e20240290
ER -