Carcinoma of Unknown Primary: Diagnostics and the Potential of Transoral Surgery

Stijn Van Weert*, Jan Jaap Hendrickx, C. René Leemans

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Abstract

The topic of the unknown primary tumour in head and neck cancer (CUP) has been extensively studied. The increasing incidence of Human papillomavirus (HPV) related oropharyngeal squamous cell carcinoma (OPSCC) as well as the emerging role of transoral robotic surgery (TORS) has led to revision and evolution of diagnostic and treatment paradigms. The concept of tongue base mucosectomy (TBM) has gained its place in the diagnostic pathway. The most recent considerations are described herein with regard to recent literature. An algorithm for patients with CUP is proposed with an emphasis on the role of transoral surgery.
Original languageEnglish
Title of host publicationCritical Issues in Head and Neck Oncology: Key Concepts from the Eighth THNO Meeting
Subtitle of host publicationKey Concepts from the Eighth THNO Meeting
EditorsJan B. Vermorken, Volker Budach, C. René Leemans, Jean-Pascal Machiels, Piero Nicolai, Brian O'Sullivan
PublisherSpringer International Publishing
Pages179-197
Number of pages19
Volume1
Edition1
ISBN (Electronic)9783031231759
ISBN (Print)9783031231742
DOIs
Publication statusPublished - 1 Jan 2023

Keywords

  • Head and neck
  • Tongue base mucosectomy
  • Unknown primary

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