Can the preterm lung recover from perinatal stress?

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

After birth, adequate lung function is necessary for the successful adaptation of a preterm baby. Both prenatal and postnatal insults and therapeutic interventions have an immediate effect on lung function and gas exchange but also interfere with fetal and neonatal lung development. Prenatal insults like chorioamnionitis and prenatal interventions like maternal glucocorticosteroids interact but might also determine the preterm baby's lung response to postnatal interventions ("second hit") like supplementation of oxygen and drug therapy. We review current experimental and clinical findings on the influence of different perinatal factors on preterm lung development and discuss how well-established interventions in neonatal care might be adapted to attenuate postnatal lung injury.
Original languageEnglish
Article number15
JournalMolecular and Cellular Pediatrics
Volume3
Issue number1
DOIs
Publication statusPublished - 2016

Cite this

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title = "Can the preterm lung recover from perinatal stress?",
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language = "English",
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}

Can the preterm lung recover from perinatal stress? / Hütten, Matthias; Wolfs, Tim; Kramer, Boris.

In: Molecular and Cellular Pediatrics, Vol. 3, No. 1, 15, 2016.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Kramer, Boris

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JO - Molecular and Cellular Pediatrics

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