CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis

Amanda C. Doran, Lale Ozcan, Bishuang Cai, Ze Zheng, Gabrielle Fredman, Christina C. Rymond, Bernhard Dorweiler, Judith C. Sluimer, Joanne Hsieh, George Kuriakose, Alan R. Tall, Ira Tabas*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)4075-4089
Number of pages15
JournalJournal of Clinical Investigation
Volume127
Issue number11
DOIs
Publication statusPublished - 1 Nov 2017

Keywords

  • ENDOPLASMIC-RETICULUM STRESS
  • APOPTOTIC CELL ACCUMULATION
  • C/EBP HOMOLOGOUS PROTEIN
  • APOE-DEFICIENT MICE
  • LIVER-X-RECEPTOR
  • KINASE-II
  • LIPID MEDIATORS
  • PHAGOCYTOSIS
  • INFLAMMATION
  • RESOLUTION

Cite this

Doran, A. C., Ozcan, L., Cai, B., Zheng, Z., Fredman, G., Rymond, C. C., Dorweiler, B., Sluimer, J. C., Hsieh, J., Kuriakose, G., Tall, A. R., & Tabas, I. (2017). CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. Journal of Clinical Investigation, 127(11), 4075-4089. https://doi.org/10.1172/JCI94735