C-reactive protein point-of-care testing for lower respiratory tract infections: a qualitative evaluation of experiences by GPs

Jochen W. L. Cals*, Fleur H. F. Chappin, Rogier M. Hopstaken, Mirjam E. van Leeuwen, Kerenza Hood, Christopher C. Butler, Geert-Jan Dinant

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Methods. Semi-structured interview study with 20 GPs who participated in the IMPAC(3)T randomized trial evaluating the effect of GP use of CRP POCT on management of LRTI. Main outcomes were GPs' experiences and views about CRP POCT in general practice, including its role in guiding antibiotic prescribing decisions and applicability and implementation in daily practice. Results. GPs expressed mainly positive attitudes. Test results were rapidly available to support diagnostic and therapeutic processes for LRTI and other common infections, enhancing patient and GP confidence in prescribing decisions and empowering GPs to prescribe antibiotics less often. GPs were concerned about responding to ambiguous test results. They regarded financial reimbursement for using the test as essential for successful uptake. Conclusions. GPs were generally positive about CRP POCT, and they felt that it empowered them to safely prescribe fewer antibiotics for LRTI without alienating their patients. Successful wider implementation should address reimbursement and updating management guidelines to include the place of CRP POCT.
Original languageEnglish
Pages (from-to)212-218
JournalFamily Practice
Issue number2
Publication statusPublished - Apr 2010


  • C-reactive protein
  • general practice
  • qualitative study
  • repiratory tract infection

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