Burst and Tonic Spinal Cord Stimulation Both Activate Spinal GABAergic Mechanisms to Attenuate Pain in a Rat Model of Chronic Neuropathic Pain

Koen P. Meuwissen*, Luuk E. de Vries, Jianwen Wendy Gu, Tianhe C. Zhang, Elbert A. J. Joosten

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)75-87
Number of pages13
JournalPain Practice
Volume20
Issue number1
Early online date9 Sep 2019
DOIs
Publication statusPublished - Jan 2020

Keywords

  • gamma-aminobutyric acid
  • burst spinal cord stimulation
  • GABAA
  • Breceptor antagonist
  • peripheral nerve injury
  • mechanical hypersensitivity
  • DESIGN ELIMINATING CONFUSION
  • GAMMA-AMINOBUTYRIC-ACID
  • TOUCH-EVOKED ALLODYNIA
  • DORSAL-HORN
  • FUNDAMENTAL DIFFERENCES
  • PERIPHERAL NEUROPATHY
  • TACTILE ALLODYNIA
  • ANIMAL-MODELS
  • FREQUENCY
  • HYPERSENSITIVITY

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