Burden of respiratory syncytial virus bronchiolitis on the Dutch pediatric intensive care units

Rosalie S. Linssen; Reinout A. Bem; Berber Kapitein; Katrien Oude Rengerink; Marieke H. Otten; Bibiche den Hollander; Louis Bont; Job B. M. van Woensel; PICE Study Group; Dick van Waardenburg

doi:10.1007/s00431-021-04079-y

Burden of respiratory syncytial virus bronchiolitis on the Dutch pediatric intensive care units

Rosalie S. Linssen^*, Reinout A. Bem, Berber Kapitein, Katrien Oude Rengerink, Marieke H. Otten, Bibiche den Hollander, Louis Bont, Job B. M. van Woensel, PICE Study Group, Dick van Waardenburg

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

8 Citations (Web of Science)

Abstract

Respiratory syncytial virus (RSV) bronchiolitis causes substantial morbidity and mortality in young children, but insight into the burden of RSV bronchiolitis on pediatric intensive care units (PICUs) is limited. We aimed to determine the burden of RSV bronchiolitis on the PICUs in the Netherlands. Therefore, we identified all children

Conclusion: The burden of severe RSV bronchiolitis on PICUs has increased in the Netherlands. Concomitantly, the use of non-invasive respiratory support, especially HFNC, has increased.

What is Known:

center dot RSV bronchiolitis is a major cause of childhood morbidity and mortality and may require pediatric intensive care unit admission.

center dot The field of pediatric critical care for severe bronchiolitis has changed due to increased non-invasive respiratory support options.

What is New:

center dot The burden of RSV bronchiolitis for the Dutch PICUs has increased. These data inform future strategic PICU resource planning and implementation of RSV preventive strategies.

center dot There was a significant increase in the use of high flow nasal cannula at the PICU, but the use of invasive mechanical ventilation did not decrease.

Original language	English
Pages (from-to)	3141-3149
Number of pages	9
Journal	European Journal of Pediatrics
Volume	180
Issue number	10
DOIs	https://doi.org/10.1007/s00431-021-04079-y
Publication status	Published - Oct 2021

Keywords

Airway management
Child
Bronchiolitis
High flow nasal cannula
Non-invasive ventilation
Respiratory syncytial viruses
Vaccination
CHILDREN
INFANTS
INTUBATION
PREVENTION
DISEASE
OXYGEN

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10.1007/s00431-021-04079-y

Cite this

@article{be7332f1f19c47e5bc64c06065393e31,

title = "Burden of respiratory syncytial virus bronchiolitis on the Dutch pediatric intensive care units",

abstract = "Respiratory syncytial virus (RSV) bronchiolitis causes substantial morbidity and mortality in young children, but insight into the burden of RSV bronchiolitis on pediatric intensive care units (PICUs) is limited. We aimed to determine the burden of RSV bronchiolitis on the PICUs in the Netherlands. Therefore, we identified all childrenConclusion: The burden of severe RSV bronchiolitis on PICUs has increased in the Netherlands. Concomitantly, the use of non-invasive respiratory support, especially HFNC, has increased.What is Known:center dot RSV bronchiolitis is a major cause of childhood morbidity and mortality and may require pediatric intensive care unit admission.center dot The field of pediatric critical care for severe bronchiolitis has changed due to increased non-invasive respiratory support options.What is New:center dot The burden of RSV bronchiolitis for the Dutch PICUs has increased. These data inform future strategic PICU resource planning and implementation of RSV preventive strategies.center dot There was a significant increase in the use of high flow nasal cannula at the PICU, but the use of invasive mechanical ventilation did not decrease.",

keywords = "Airway management, Child, Bronchiolitis, High flow nasal cannula, Non-invasive ventilation, Respiratory syncytial viruses, Vaccination, CHILDREN, INFANTS, INTUBATION, PREVENTION, DISEASE, OXYGEN",

author = "Linssen, {Rosalie S.} and Bem, {Reinout A.} and Berber Kapitein and Rengerink, {Katrien Oude} and Otten, {Marieke H.} and {den Hollander}, Bibiche and Louis Bont and {van Woensel}, {Job B. M.} and {PICE Study Group} and {van Waardenburg}, Dick",

year = "2021",

month = oct,

doi = "10.1007/s00431-021-04079-y",

language = "English",

volume = "180",

pages = "3141--3149",

journal = "European Journal of Pediatrics",

issn = "0340-6199",

publisher = "Springer, Cham",

number = "10",

}

TY - JOUR

T1 - Burden of respiratory syncytial virus bronchiolitis on the Dutch pediatric intensive care units

AU - Linssen, Rosalie S.

AU - Bem, Reinout A.

AU - Kapitein, Berber

AU - Rengerink, Katrien Oude

AU - Otten, Marieke H.

AU - den Hollander, Bibiche

AU - Bont, Louis

AU - van Woensel, Job B. M.

AU - PICE Study Group

AU - van Waardenburg, Dick

PY - 2021/10

Y1 - 2021/10

N2 - Respiratory syncytial virus (RSV) bronchiolitis causes substantial morbidity and mortality in young children, but insight into the burden of RSV bronchiolitis on pediatric intensive care units (PICUs) is limited. We aimed to determine the burden of RSV bronchiolitis on the PICUs in the Netherlands. Therefore, we identified all childrenConclusion: The burden of severe RSV bronchiolitis on PICUs has increased in the Netherlands. Concomitantly, the use of non-invasive respiratory support, especially HFNC, has increased.What is Known:center dot RSV bronchiolitis is a major cause of childhood morbidity and mortality and may require pediatric intensive care unit admission.center dot The field of pediatric critical care for severe bronchiolitis has changed due to increased non-invasive respiratory support options.What is New:center dot The burden of RSV bronchiolitis for the Dutch PICUs has increased. These data inform future strategic PICU resource planning and implementation of RSV preventive strategies.center dot There was a significant increase in the use of high flow nasal cannula at the PICU, but the use of invasive mechanical ventilation did not decrease.

AB - Respiratory syncytial virus (RSV) bronchiolitis causes substantial morbidity and mortality in young children, but insight into the burden of RSV bronchiolitis on pediatric intensive care units (PICUs) is limited. We aimed to determine the burden of RSV bronchiolitis on the PICUs in the Netherlands. Therefore, we identified all childrenConclusion: The burden of severe RSV bronchiolitis on PICUs has increased in the Netherlands. Concomitantly, the use of non-invasive respiratory support, especially HFNC, has increased.What is Known:center dot RSV bronchiolitis is a major cause of childhood morbidity and mortality and may require pediatric intensive care unit admission.center dot The field of pediatric critical care for severe bronchiolitis has changed due to increased non-invasive respiratory support options.What is New:center dot The burden of RSV bronchiolitis for the Dutch PICUs has increased. These data inform future strategic PICU resource planning and implementation of RSV preventive strategies.center dot There was a significant increase in the use of high flow nasal cannula at the PICU, but the use of invasive mechanical ventilation did not decrease.

KW - Airway management

KW - Child

KW - Bronchiolitis

KW - High flow nasal cannula

KW - Non-invasive ventilation

KW - Respiratory syncytial viruses

KW - Vaccination

KW - CHILDREN

KW - INFANTS

KW - INTUBATION

KW - PREVENTION

KW - DISEASE

KW - OXYGEN

U2 - 10.1007/s00431-021-04079-y

DO - 10.1007/s00431-021-04079-y

M3 - Article

C2 - 33891158

SN - 0340-6199

VL - 180

SP - 3141

EP - 3149

JO - European Journal of Pediatrics

JF - European Journal of Pediatrics

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ER -