@article{4e156e1d5c7c488cbaa1ffd9109b6683,
title = "Burden of disease of type 2 diabetes mellitus: cost of illness and quality of life estimated using the Maastricht Study",
abstract = "Aims To estimate the societal costs and quality of life of people with type 2 diabetes and to compare these results with those of people with normal glucose tolerance or prediabetes.Methods Data from 2915 individuals from the population-based Maastricht Study were included. Costs were assessed through a resource-use questionnaire completed by the participants; cost prices were based on Dutch costing guidelines. Quality of life was expressed in utilities using the Dutch EuroQol 5D-3L questionnaire and the SF-36 health survey. Based on normal fasting glucose and 2-h plasma glucose values, participants were classified into three groups: normal glucose tolerance (n = 1701); prediabetes (n = 446); or type 2 diabetes (n = 768).Results Participants with type 2 diabetes had on average 2.2 times higher societal costs than those with normal glucose tolerance (euro3,006 and euro1,377 per 6 months, respectively) and had lower utilities (0.77 and 0.81, respectively). No significant differences were found between participants with normal glucose tolerance and those with prediabetes. Subgroup analyses showed that higher age, being female and having two or more diabetes-related complications resulted in higher costs (P <0.05) and lower utilities.Conclusions This study showed that people with type 2 diabetes have substantially higher societal costs and lower quality of life than people with normal glucose tolerance. The results provide important input for future model-based economic evaluations and for policy decision-making.",
keywords = "HEALTH-CARE COSTS, GLYCEMIC CONTROL, COMPLICATIONS, PEOPLE",
author = "Janssen, {L. M. M.} and M. Hiligsmann and Elissen, {A. M. J.} and Joore, {M. A.} and Schaper, {N. C.} and Bosma, {J. H. A.} and Stehouwer, {C. D. A.} and Sep, {S. J. S.} and A. Koster and Schram, {M. T.} and Evers, {S. M. A. A.}",
note = "Funding Information: This study was supported by the European Regional Development Fund via OP‐Zuid, the Province of Limburg, the Dutch Ministry of Economic Affairs (grant 31O.041), Stichting De Weijerhorst (Maastricht, The Netherlands), the Pearl String Initiative Diabetes (Amsterdam, The Netherlands), the Cardiovascular Centre (CVC, Maastricht, the Netherlands), CARIM School for Cardiovascular Diseases (Maastricht, The Netherlands), CAPHRI Care and Public Health Research Institute (Maastricht, The Netherlands), NUTRIM School for Nutrition and Translational Research in Metabolism (Maastricht, The Netherlands), Stichting Annadal (Maastricht, The Netherlands), Health Foundation Limburg (Maastricht, The Netherlands), and by unrestricted grants from Janssen‐Cilag B.V. (Tilburg, The Netherlands), Novo Nordisk Farma B.V. (Alphen aan den Rijn, The Netherlands), and Sanofi‐Aventis Netherlands B.V. (Gouda, The Netherlands). Funding Information: This study was supported by the European Regional Development Fund via OP-Zuid, the Province of Limburg, the Dutch Ministry of Economic Affairs (grant 31O.041), Stichting De Weijerhorst (Maastricht, The Netherlands), the Pearl String Initiative Diabetes (Amsterdam, The Netherlands), the Cardiovascular Centre (CVC, Maastricht, the Netherlands), CARIM School for Cardiovascular Diseases (Maastricht, The Netherlands), CAPHRI Care and Public Health Research Institute (Maastricht, The Netherlands), NUTRIM School for Nutrition and Translational Research in Metabolism (Maastricht, The Netherlands), Stichting Annadal (Maastricht, The Netherlands), Health Foundation Limburg (Maastricht, The Netherlands), and by unrestricted grants from Janssen-Cilag B.V. (Tilburg, The Netherlands), Novo Nordisk Farma B.V. (Alphen aan den Rijn, The Netherlands), and Sanofi-Aventis Netherlands B.V. (Gouda, The Netherlands). Publisher Copyright: {\textcopyright} 2020 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK",
year = "2020",
month = oct,
doi = "10.1111/dme.14285",
language = "English",
volume = "37",
pages = "1759--1765",
journal = "Diabetic Medicine",
issn = "0742-3071",
publisher = "Wiley-Blackwell",
number = "10",
}