BRCA1 and BRCA2 genetic testing-pitfalls and recommendations for managing variants of uncertain clinical significance

D. M. Eccles; G. Mitchell; A. N. A. Monteiro; R. Schmutzler; F. J. Couch; A. B. Spurdle; E. B. Gomez-Garcia

doi:10.1093/annonc/mdv278

BRCA1 and BRCA2 genetic testing-pitfalls and recommendations for managing variants of uncertain clinical significance

D. M. Eccles, G. Mitchell, A. N. A. Monteiro, R. Schmutzler, F. J. Couch, A. B. Spurdle, E. B. Gomez-Garcia^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

112 Citations (Web of Science)

Original language	English
Pages (from-to)	2057-2065
Journal	Annals of Oncology
Volume	26
Issue number	10
DOIs	https://doi.org/10.1093/annonc/mdv278
Publication status	Published - Oct 2015

Keywords

variants of uncertain significance
VUS
BRCA
clinical utility
classification

Access to Document

10.1093/annonc/mdv278

Cite this

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title = "BRCA1 and BRCA2 genetic testing-pitfalls and recommendations for managing variants of uncertain clinical significance",

keywords = "variants of uncertain significance, VUS, BRCA, clinical utility, classification",

author = "Eccles, {D. M.} and G. Mitchell and Monteiro, {A. N. A.} and R. Schmutzler and Couch, {F. J.} and Spurdle, {A. B.} and Gomez-Garcia, {E. B.}",

year = "2015",

month = oct,

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volume = "26",

pages = "2057--2065",

journal = "Annals of Oncology",

issn = "0923-7534",

publisher = "Oxford University Press",

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}

BRCA1 and BRCA2 genetic testing-pitfalls and recommendations for managing variants of uncertain clinical significance. / Eccles, D. M.; Mitchell, G.; Monteiro, A. N. A.; Schmutzler, R.; Couch, F. J.; Spurdle, A. B.; Gomez-Garcia, E. B.

In: Annals of Oncology, Vol. 26, No. 10, 10.2015, p. 2057-2065.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - BRCA1 and BRCA2 genetic testing-pitfalls and recommendations for managing variants of uncertain clinical significance

AU - Eccles, D. M.

AU - Mitchell, G.

AU - Monteiro, A. N. A.

AU - Schmutzler, R.

AU - Couch, F. J.

AU - Spurdle, A. B.

AU - Gomez-Garcia, E. B.

PY - 2015/10

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KW - variants of uncertain significance

KW - VUS

KW - BRCA

KW - clinical utility

KW - classification

U2 - 10.1093/annonc/mdv278

DO - 10.1093/annonc/mdv278

M3 - Article

VL - 26

SP - 2057

EP - 2065

JO - Annals of Oncology

JF - Annals of Oncology

SN - 0923-7534

IS - 10

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