Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: a double-blind, randomized trial

Cas J. Fuchs; Wesley J. H. Hermans; Andrew M. Holwerda; Joey S. J. Smeets; Joan M. Senden; Janneau van Kranenburg; Annemie P. Gijsen; Will K. H. W. Wodzig; Henk Schierbeek; Lex B. Verdijk; Luc J. C. van Loon

doi:10.1093/ajcn/nqz120

Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: a double-blind, randomized trial

Cas J. Fuchs, Wesley J. H. Hermans, Andrew M. Holwerda, Joey S. J. Smeets, Joan M. Senden, Janneau van Kranenburg, Annemie P. Gijsen, Will K. H. W. Wodzig, Henk Schierbeek, Lex B. Verdijk, Luc J. C. van Loon^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	862-872
Number of pages	11
Journal	American Journal of Clinical Nutrition
Volume	110
Issue number	4
DOIs	https://doi.org/10.1093/ajcn/nqz120
Publication status	Published - Oct 2019

Keywords

aging
sarcopenia
chronic kidney disease
anabolism
milk
dietary protein
leucine
alpha-ketoisocaproic acid
SKELETAL-MUSCLE
DIETARY-PROTEIN
HEALTHY OLDER
ALPHA-KETOISOCAPROATE
NITROGEN-METABOLISM
LEUCINE
SUPPLEMENTATION
STIMULATION
ABSORPTION
RESPONSES

Cite this

Fuchs, C. J., Hermans, W. J. H., Holwerda, A. M., Smeets, J. S. J., Senden, J. M., van Kranenburg, J., Gijsen, A. P., Wodzig, W. K. H. W., Schierbeek, H., Verdijk, L. B., & van Loon, L. J. C. (2019). Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: a double-blind, randomized trial. American Journal of Clinical Nutrition, 110(4), 862-872. https://doi.org/10.1093/ajcn/nqz120

Fuchs, Cas J. ; Hermans, Wesley J. H. ; Holwerda, Andrew M. ; Smeets, Joey S. J. ; Senden, Joan M. ; van Kranenburg, Janneau ; Gijsen, Annemie P. ; Wodzig, Will K. H. W. ; Schierbeek, Henk ; Verdijk, Lex B. ; van Loon, Luc J. C. / Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults : a double-blind, randomized trial. In: American Journal of Clinical Nutrition. 2019 ; Vol. 110, No. 4. pp. 862-872.

@article{3c849f08569a42c787164408661849a1,

title = "Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: a double-blind, randomized trial",

keywords = "aging, sarcopenia, chronic kidney disease, anabolism, milk, dietary protein, leucine, alpha-ketoisocaproic acid, SKELETAL-MUSCLE, DIETARY-PROTEIN, HEALTHY OLDER, ALPHA-KETOISOCAPROATE, NITROGEN-METABOLISM, LEUCINE, SUPPLEMENTATION, STIMULATION, ABSORPTION, RESPONSES",

author = "Fuchs, {Cas J.} and Hermans, {Wesley J. H.} and Holwerda, {Andrew M.} and Smeets, {Joey S. J.} and Senden, {Joan M.} and {van Kranenburg}, Janneau and Gijsen, {Annemie P.} and Wodzig, {Will K. H. W.} and Henk Schierbeek and Verdijk, {Lex B.} and {van Loon}, {Luc J. C.}",

year = "2019",

month = oct

doi = "10.1093/ajcn/nqz120",

language = "English",

volume = "110",

pages = "862--872",

journal = "American Journal of Clinical Nutrition",

issn = "0002-9165",

publisher = "Oxford University Press",

number = "4",

}

Fuchs, CJ, Hermans, WJH, Holwerda, AM , Smeets, JSJ , Senden, JM , van Kranenburg, J , Gijsen, AP , Wodzig, WKHW, Schierbeek, H, Verdijk, LB & van Loon, LJC 2019, 'Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: a double-blind, randomized trial', American Journal of Clinical Nutrition, vol. 110, no. 4, pp. 862-872. https://doi.org/10.1093/ajcn/nqz120

Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults : a double-blind, randomized trial. / Fuchs, Cas J.; Hermans, Wesley J. H.; Holwerda, Andrew M.; Smeets, Joey S. J.; Senden, Joan M.; van Kranenburg, Janneau ; Gijsen, Annemie P.; Wodzig, Will K. H. W.; Schierbeek, Henk; Verdijk, Lex B.; van Loon, Luc J. C.

In: American Journal of Clinical Nutrition, Vol. 110, No. 4, 10.2019, p. 862-872.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults

T2 - a double-blind, randomized trial

AU - Fuchs, Cas J.

AU - Hermans, Wesley J. H.

AU - Holwerda, Andrew M.

AU - Smeets, Joey S. J.

AU - Senden, Joan M.

AU - van Kranenburg, Janneau

AU - Gijsen, Annemie P.

AU - Wodzig, Will K. H. W.

AU - Schierbeek, Henk

AU - Verdijk, Lex B.

AU - van Loon, Luc J. C.

PY - 2019/10

Y1 - 2019/10

KW - aging

KW - sarcopenia

KW - chronic kidney disease

KW - anabolism

KW - milk

KW - dietary protein

KW - leucine

KW - alpha-ketoisocaproic acid

KW - SKELETAL-MUSCLE

KW - DIETARY-PROTEIN

KW - HEALTHY OLDER

KW - ALPHA-KETOISOCAPROATE

KW - NITROGEN-METABOLISM

KW - LEUCINE

KW - SUPPLEMENTATION

KW - STIMULATION

KW - ABSORPTION

KW - RESPONSES

U2 - 10.1093/ajcn/nqz120

DO - 10.1093/ajcn/nqz120

M3 - Article

VL - 110

SP - 862

EP - 872

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

SN - 0002-9165

IS - 4

ER -

Access to Document

10.1093/ajcn/nqz120