Blood Pressure Load Does Not Add to Ambulatory Blood Pressure Level for Cardiovascular Risk Stratification

Yan Li; Lutgarde Thijs; Jose Boggia; Kei Asayama; Tine W. Hansen; Masahiro Kikuya; Kristina Bjorklund-Bodegard; Takayoshi Ohkubo; Jorgen Jeppesen; Christian Torp-Pedersen; Eamon Dolan; Tatiana Kuznetsova; Katarzyna Stolarz-Skrzypek; Valerie Tikhonoff; Sofia Malyutina; Edoardo Casiglia; Yuri Nikitin; Lars Lind; Edgardo Sandoya; Kalina Kawecka-Jaszcz; Jan Filipovsky; Yutaka Imai; Hans Ibsen; Eoin O'Brien; Jiguang Wang; Jan A. Staessen

doi:10.1161/HYPERTENSIONAHA.113.02780

Blood Pressure Load Does Not Add to Ambulatory Blood Pressure Level for Cardiovascular Risk Stratification

Yan Li, Lutgarde Thijs, Jose Boggia, Kei Asayama, Tine W. Hansen, Masahiro Kikuya, Kristina Bjorklund-Bodegard, Takayoshi Ohkubo, Jorgen Jeppesen, Christian Torp-Pedersen, Eamon Dolan, Tatiana Kuznetsova, Katarzyna Stolarz-Skrzypek, Valerie Tikhonoff, Sofia Malyutina, Edoardo Casiglia, Yuri Nikitin, Lars Lind, Edgardo Sandoya, Kalina Kawecka-JaszczJan Filipovsky, Yutaka Imai, Hans Ibsen, Eoin O'Brien, Jiguang Wang, Jan A. Staessen^*

^*Corresponding author for this work

Epidemiologie

Research output: Contribution to journal › Article › Academic › peer-review

28 Citations (Web of Science)

Abstract

Experts proposed blood pressure (BP) load derived from 24-hour ambulatory BP recordings as a more accurate predictor of outcome than level, in particular in normotensive people. We analyzed 8711 subjects (mean age, 54.8 years; 47.0% women) randomly recruited from 10 populations. We expressed BP load as percentage (%) of systolic/diastolic readings 135/85 mm Hg and 120/70 mm Hg during day and night, respectively, or as the area under the BP curve (mm Hgxh) using the same ceiling values. During a period of 10.7 years (median), 1284 participants died and 1109 experienced a fatal or nonfatal cardiovascular end point. In multivariable-adjusted models, the risk of cardiovascular complications gradually increased across deciles of BP level and load (P

Original language	English
Pages (from-to)	925-933
Journal	Hypertension
Volume	63
Issue number	5
DOIs	https://doi.org/10.1161/HYPERTENSIONAHA.113.02780
Publication status	Published - May 2014

Keywords

ambulatory blood pressure monitoring
epidemiology
risk factors

Access to Document

10.1161/HYPERTENSIONAHA.113.02780

Cite this

Li, Y., Thijs, L., Boggia, J., Asayama, K., Hansen, T. W., Kikuya, M., Bjorklund-Bodegard, K., Ohkubo, T., Jeppesen, J., Torp-Pedersen, C., Dolan, E., Kuznetsova, T., Stolarz-Skrzypek, K., Tikhonoff, V., Malyutina, S., Casiglia, E., Nikitin, Y., Lind, L., Sandoya, E., ... Staessen, J. A. (2014). Blood Pressure Load Does Not Add to Ambulatory Blood Pressure Level for Cardiovascular Risk Stratification. Hypertension, 63(5), 925-933. https://doi.org/10.1161/HYPERTENSIONAHA.113.02780

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abstract = "Experts proposed blood pressure (BP) load derived from 24-hour ambulatory BP recordings as a more accurate predictor of outcome than level, in particular in normotensive people. We analyzed 8711 subjects (mean age, 54.8 years; 47.0% women) randomly recruited from 10 populations. We expressed BP load as percentage (%) of systolic/diastolic readings 135/85 mm Hg and 120/70 mm Hg during day and night, respectively, or as the area under the BP curve (mm Hgxh) using the same ceiling values. During a period of 10.7 years (median), 1284 participants died and 1109 experienced a fatal or nonfatal cardiovascular end point. In multivariable-adjusted models, the risk of cardiovascular complications gradually increased across deciles of BP level and load (P",

keywords = "ambulatory blood pressure monitoring, epidemiology, risk factors",

author = "Yan Li and Lutgarde Thijs and Jose Boggia and Kei Asayama and Hansen, {Tine W.} and Masahiro Kikuya and Kristina Bjorklund-Bodegard and Takayoshi Ohkubo and Jorgen Jeppesen and Christian Torp-Pedersen and Eamon Dolan and Tatiana Kuznetsova and Katarzyna Stolarz-Skrzypek and Valerie Tikhonoff and Sofia Malyutina and Edoardo Casiglia and Yuri Nikitin and Lars Lind and Edgardo Sandoya and Kalina Kawecka-Jaszcz and Jan Filipovsky and Yutaka Imai and Hans Ibsen and Eoin O'Brien and Jiguang Wang and Staessen, {Jan A.}",

year = "2014",

month = may,

doi = "10.1161/HYPERTENSIONAHA.113.02780",

language = "English",

volume = "63",

pages = "925--933",

journal = "Hypertension",

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Li, Y, Thijs, L, Boggia, J, Asayama, K, Hansen, TW, Kikuya, M, Bjorklund-Bodegard, K, Ohkubo, T, Jeppesen, J, Torp-Pedersen, C, Dolan, E, Kuznetsova, T, Stolarz-Skrzypek, K, Tikhonoff, V, Malyutina, S, Casiglia, E, Nikitin, Y, Lind, L, Sandoya, E, Kawecka-Jaszcz, K, Filipovsky, J, Imai, Y, Ibsen, H, O'Brien, E, Wang, J & Staessen, JA 2014, 'Blood Pressure Load Does Not Add to Ambulatory Blood Pressure Level for Cardiovascular Risk Stratification', Hypertension, vol. 63, no. 5, pp. 925-933. https://doi.org/10.1161/HYPERTENSIONAHA.113.02780

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T1 - Blood Pressure Load Does Not Add to Ambulatory Blood Pressure Level for Cardiovascular Risk Stratification

AU - Li, Yan

AU - Thijs, Lutgarde

AU - Boggia, Jose

AU - Asayama, Kei

AU - Hansen, Tine W.

AU - Kikuya, Masahiro

AU - Bjorklund-Bodegard, Kristina

AU - Ohkubo, Takayoshi

AU - Jeppesen, Jorgen

AU - Torp-Pedersen, Christian

AU - Dolan, Eamon

AU - Kuznetsova, Tatiana

AU - Stolarz-Skrzypek, Katarzyna

AU - Tikhonoff, Valerie

AU - Malyutina, Sofia

AU - Casiglia, Edoardo

AU - Nikitin, Yuri

AU - Lind, Lars

AU - Sandoya, Edgardo

AU - Kawecka-Jaszcz, Kalina

AU - Filipovsky, Jan

AU - Imai, Yutaka

AU - Ibsen, Hans

AU - O'Brien, Eoin

AU - Wang, Jiguang

AU - Staessen, Jan A.

PY - 2014/5

Y1 - 2014/5

N2 - Experts proposed blood pressure (BP) load derived from 24-hour ambulatory BP recordings as a more accurate predictor of outcome than level, in particular in normotensive people. We analyzed 8711 subjects (mean age, 54.8 years; 47.0% women) randomly recruited from 10 populations. We expressed BP load as percentage (%) of systolic/diastolic readings 135/85 mm Hg and 120/70 mm Hg during day and night, respectively, or as the area under the BP curve (mm Hgxh) using the same ceiling values. During a period of 10.7 years (median), 1284 participants died and 1109 experienced a fatal or nonfatal cardiovascular end point. In multivariable-adjusted models, the risk of cardiovascular complications gradually increased across deciles of BP level and load (P

AB - Experts proposed blood pressure (BP) load derived from 24-hour ambulatory BP recordings as a more accurate predictor of outcome than level, in particular in normotensive people. We analyzed 8711 subjects (mean age, 54.8 years; 47.0% women) randomly recruited from 10 populations. We expressed BP load as percentage (%) of systolic/diastolic readings 135/85 mm Hg and 120/70 mm Hg during day and night, respectively, or as the area under the BP curve (mm Hgxh) using the same ceiling values. During a period of 10.7 years (median), 1284 participants died and 1109 experienced a fatal or nonfatal cardiovascular end point. In multivariable-adjusted models, the risk of cardiovascular complications gradually increased across deciles of BP level and load (P

KW - ambulatory blood pressure monitoring

KW - epidemiology

KW - risk factors

U2 - 10.1161/HYPERTENSIONAHA.113.02780

DO - 10.1161/HYPERTENSIONAHA.113.02780

M3 - Article

C2 - 24535008

VL - 63

SP - 925

EP - 933

JO - Hypertension

JF - Hypertension

SN - 0194-911X

IS - 5

ER -