TY - JOUR
T1 - Blood Pressure Load Does Not Add to Ambulatory Blood Pressure Level for Cardiovascular Risk Stratification
AU - Li, Yan
AU - Thijs, Lutgarde
AU - Boggia, Jose
AU - Asayama, Kei
AU - Hansen, Tine W.
AU - Kikuya, Masahiro
AU - Bjorklund-Bodegard, Kristina
AU - Ohkubo, Takayoshi
AU - Jeppesen, Jorgen
AU - Torp-Pedersen, Christian
AU - Dolan, Eamon
AU - Kuznetsova, Tatiana
AU - Stolarz-Skrzypek, Katarzyna
AU - Tikhonoff, Valerie
AU - Malyutina, Sofia
AU - Casiglia, Edoardo
AU - Nikitin, Yuri
AU - Lind, Lars
AU - Sandoya, Edgardo
AU - Kawecka-Jaszcz, Kalina
AU - Filipovsky, Jan
AU - Imai, Yutaka
AU - Ibsen, Hans
AU - O'Brien, Eoin
AU - Wang, Jiguang
AU - Staessen, Jan A.
PY - 2014/5
Y1 - 2014/5
N2 - Experts proposed blood pressure (BP) load derived from 24-hour ambulatory BP recordings as a more accurate predictor of outcome than level, in particular in normotensive people. We analyzed 8711 subjects (mean age, 54.8 years; 47.0% women) randomly recruited from 10 populations. We expressed BP load as percentage (%) of systolic/diastolic readings 135/85 mm Hg and 120/70 mm Hg during day and night, respectively, or as the area under the BP curve (mm Hgxh) using the same ceiling values. During a period of 10.7 years (median), 1284 participants died and 1109 experienced a fatal or nonfatal cardiovascular end point. In multivariable-adjusted models, the risk of cardiovascular complications gradually increased across deciles of BP level and load (P
AB - Experts proposed blood pressure (BP) load derived from 24-hour ambulatory BP recordings as a more accurate predictor of outcome than level, in particular in normotensive people. We analyzed 8711 subjects (mean age, 54.8 years; 47.0% women) randomly recruited from 10 populations. We expressed BP load as percentage (%) of systolic/diastolic readings 135/85 mm Hg and 120/70 mm Hg during day and night, respectively, or as the area under the BP curve (mm Hgxh) using the same ceiling values. During a period of 10.7 years (median), 1284 participants died and 1109 experienced a fatal or nonfatal cardiovascular end point. In multivariable-adjusted models, the risk of cardiovascular complications gradually increased across deciles of BP level and load (P
KW - ambulatory blood pressure monitoring
KW - epidemiology
KW - risk factors
U2 - 10.1161/HYPERTENSIONAHA.113.02780
DO - 10.1161/HYPERTENSIONAHA.113.02780
M3 - Article
C2 - 24535008
SN - 0194-911X
VL - 63
SP - 925
EP - 933
JO - Hypertension
JF - Hypertension
IS - 5
ER -