Blood pressure and cerebral small vessel disease

P. Klarenbeek

Research output: ThesisDoctoral ThesisInternal


Cerebral small vessel disease (cSVD) is a condition affecting the small blood vessels in the body and can lead to cerebral infarction in the deeper parts of the brain, also known as a lacunar stroke. We researched the relationship between 24-hour blood pressure tests and cSVD expressions in an MRI scan of patients with a recent lacunar stroke. One key finding was a link between blood pressure, spaces around blood vessels (perivascular areas) and microbleeds. Blood pressure was also associated with a new score we developed that combines all cSVD expressions on an MRI scan. This score offers a new way of examining the overall severity of cSVD on an MRI scan, which had never been done before.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
  • van Oostenbrugge, Robert Jan, Supervisor
  • Staals, Julie, Co-Supervisor
Award date29 Jan 2016
Publication statusPublished - 1 Jan 2016


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