Biopsychosocial rehabilitation therapy in small fiber neuropathy: research protocol to study the effect of rehabilitation treatment

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Abstract

Background Small fiber neuropathy (SFN) is a chronic neuropathic pain condition that can lead to a decreased quality of life (QOL) and disability. Current pain treatment is mainly symptomatic, consisting of analgesics, with often disappointing results. There is a need for new, more effective treatment modality. Treatment based on a biopsychosocial approach on SFN-related pain may be a promising alternative. A rehabilitation treatment study protocol is presented with the following main objective: to test the effect of a tailored interdisciplinary rehabilitation treatment targeting both cognitive and psychological factors related to pain, in decreasing disability, and improving QOL in SFN. Methods Single-case experimental design. Ten participants with SFN will be included. Every patient will be offered a personalized program based on one of three rehabilitation treatment modules (graded activity, exposure in vivo or acceptance and commitment therapy) depending on the most prominent factor maintaining disability. Treatment will be provided for at least 8 weeks with 2 sessions a week. Discussion/conclusion This is the first study investigating personalized rehabilitation treatment in patients with idiopathic SFN. The findings are expected to result in an effective treatment for SFN with an increase in QOL and a decrease in disability. Clinical trial registration ClinicalTrials.gov, identifier NCT05798949.
Original languageEnglish
Article number1493326
Number of pages10
JournalFrontiers in Neurology
Volume15
DOIs
Publication statusPublished - 13 Nov 2024

Keywords

  • controlled clinical trial
  • rehabilitation
  • single case study
  • neuropathic pain
  • rehabilitation therapy
  • LOW-BACK-PAIN
  • QUALITY-OF-LIFE
  • RANDOMIZED CONTROLLED-TRIALS
  • SINGLE-CASE DESIGN
  • EXPOSURE IN-VIVO
  • COMMITMENT THERAPY
  • HOSPITAL ANXIETY
  • NEUROSCIENCE EDUCATION
  • MUSCULOSKELETAL PAIN
  • DEPRESSION SCALE

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