Biofabrication of Hepatic Constructs by 3D Bioprinting of a Cell-Laden Thermogel: An Effective Tool to Assess Drug-Induced Hepatotoxic Response

Manuele Gori, Sara M. Giannitelli, Miranda Torre, Pamela Mozetic, Franca Abbruzzese, Marcella Trombetta, Enrico Traversa, Lorenzo Moroni, Alberto Rainer*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number2001163
Number of pages11
JournalAdvanced Healthcare Materials
Volume9
Issue number21
Early online date17 Sep 2020
DOIs
Publication statusPublished - Nov 2020

Keywords

  • 3D liver models
  • bioprinting
  • drug hepatotoxicity
  • hepatic constructs
  • Pluronic
  • alginate thermogels
  • ACETAMINOPHEN-INDUCED HEPATOTOXICITY
  • IN-VITRO MODEL
  • CYTOCHROME-P450 INDUCTION
  • HEPG2 CELLS
  • LIVER
  • CULTURE
  • TOXICITY
  • HEPATOCYTE
  • PREDICTION
  • MECHANISMS

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