Bilateral catheter-directed thrombolysis in a patient with deep venous thrombosis caused by a hypoplastic inferior vena cava

S. Sloot, J. Van Nierop, J. J. Kootstra, C. Wittens, W. M. Fritschy*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Introduction Deep venous thrombosis treatment using catheter-directed thrombolysis is advocated over systemic thrombolysis because it reduces bleeding complications. With the development of a catheter that combines ultrasound vibrations and the local delivering of thrombolytics, new and safer treatments appear that are suitable for more complex problems. Report An adolescent male presented with bilateral iliofemoral thrombosis based on a hypoplastic inferior vena cava that had existed for more than two weeks. He was succesfully treated by bilateral ultrasound-accelerated catheter-directed thrombolysis using EkoSonic (R) (Small Vessel) Endovascular System (EKOS) and stenting of the inferior vena cava. After eight months of follow-up, the inferior vena cava is still patent. Conclusion EKOS thrombolysis of longer existing bilateral deep venous thrombosis in the central venous system is a succesful treatment modality in congenital inferior vena cava anomalies.
Original languageEnglish
Pages (from-to)293-295
JournalPhlebology: The Journal of Venous Disease
Issue number4
Publication statusPublished - May 2015


  • Deep venous thrombosis
  • ultra-sound catheter-directed thrombolysis
  • EKOS
  • inferior vena cava anomalies
  • post-thrombotic stress syndrome

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