Abstract
Radiofluorinated 4-fluorobenzonitrile oxide and N-hydroxy-4-fluorobenzimidoyl chloride rapidly react with different alkenes and alkynes under mild conditions. These cycloadditions are suitable for the preparation of low-molecular weight radiopharmaceuticals and, in a strain-promoted variant, can enable easy labelling of sensitive biopolymers.
Original language | English |
---|---|
Pages (from-to) | 7134-7136 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 48 |
Issue number | 57 |
DOIs | |
Publication status | Published - 1 Jan 2012 |
Keywords
- F-18
- PET