Baroreflex activation therapy for patients with drug-resistant hypertension

Teba Alnima, Abraham A Kroon, Peter W de Leeuw

Research output: Contribution to journalArticleAcademicpeer-review


Uncontrolled or resistant hypertension is still a major problem facing many physicians daily in the clinic. Several new therapies are being developed to help those patients whose blood pressure does not respond sufficiently to regular antihypertensive medication. One of these promising therapies is electrical activation of the carotid sinus baroreflex. In this overview, the authors predominantly summarize the background, efficacy and safety of this promising treatment with its latest achievements in patients with resistant hypertension. The authors also discuss certain issues that need further clarification before this therapy can be added to the common treatment guidelines of hypertension.

Original languageEnglish
Pages (from-to)955-62
Number of pages8
JournalExpert review of cardiovascular therapy
Issue number8
Publication statusPublished - Aug 2014


  • Animals
  • Antihypertensive Agents
  • Baroreflex
  • Carotid Sinus
  • Drug Design
  • Drug Resistance
  • Electric Stimulation Therapy
  • Humans
  • Hypertension


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