B55α/PP2A Limits Endothelial Cell Apoptosis During Vascular Remodeling: A Complementary Approach To Disrupt Pathological Vessels?

Manuel Ehling, Ward Celus, Rosa Martín-Pérez, Roser Alba-Rovira, Sander Willox, Donatella Ponti, Maria C Cid, Elizabeth A V Jones, Giusy Di Conza, Massimiliano Mazzone

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)707-723
Number of pages17
JournalCirculation Research
Volume127
Issue number6
DOIs
Publication statusPublished - 28 Aug 2020
Externally publishedYes

Keywords

  • Angiogenesis Inhibitors/pharmacology
  • Animals
  • Apoptosis
  • Breast Neoplasms/drug therapy
  • Carcinoma, Lewis Lung/drug therapy
  • Cell Line, Tumor
  • Endothelial Cells/drug effects
  • Enzyme Inhibitors/pharmacology
  • Female
  • Human Umbilical Vein Endothelial Cells/drug effects
  • Humans
  • Hypoxia-Inducible Factor-Proline Dioxygenases/genetics
  • Male
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Neovascularization, Pathologic
  • Phosphorylation
  • Protein Phosphatase 2/antagonists & inhibitors
  • Signal Transduction
  • Vascular Remodeling
  • p38 Mitogen-Activated Protein Kinases/metabolism
  • endothelial cells
  • ACTIVATION
  • METASTASIS
  • ANGIOGENESIS
  • KINASE
  • apoptosis
  • PROTEIN PHOSPHATASE 2A
  • oncology
  • INHIBITION
  • perfusion
  • developmental biology
  • VEGF
  • blood vessels
  • PP2A
  • MECHANISMS
  • P38
  • vascular endothelial growth factor

Cite this