Abstract
Autoantibodies, in particular anti-dsDNA antibodies, are increasingly used for diagnosis, classification and follow-up of patients with SLE. Since standardization of autoantibody assays is a major challenge, more attention should be paid to harmonization initiatives and better definition of required test characteristics in classification criteria. For diagnosis and follow-up separate multi-center studies are required to establish test characteristics of distinct immuno-assays for both purposes. Finally, such studies should consider not to evaluate SLE as a single disease, but as a disease with distinct subtypes.
Original language | English |
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Article number | 100191 |
Number of pages | 5 |
Journal | Journal of Translational Autoimmunity |
Volume | 6 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2023 |
Keywords
- Systemic lupus erythematosus
- anti-dsDNA
- Biomarker
- Lupus nephritis
- ANTI-C1Q AUTOANTIBODIES
- REVISED CRITERIA
- PREDICTIVE-VALUE
- ANTIBODIES
- SPECIFICITY
- BINDING