Augmenting Vacuolar H+-ATPase Function Prevents Cardiomyocytes from Lipid-Overload Induced Dysfunction

Shujin Wang, Li-Yen Wong, Dietbert Neumann, Yilin Liu, Aomin Sun, Gudrun Antoons, Agnieszka Strzelecka, Jan F. C. Glatz, Miranda Nabben, Joost J. F. P. Luiken*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number1520
Number of pages16
JournalInternational journal of molecular sciences
Volume21
Issue number4
DOIs
Publication statusPublished - Feb 2020

Keywords

  • vacuolar H+-ATPase
  • lipid accumulation
  • insulin resistance
  • contractile function
  • diabetic heart
  • ACTIVATED PROTEIN-KINASE
  • FATTY-ACID UPTAKE
  • INSULIN-RESISTANCE
  • CARDIAC MYOCYTES
  • GLUCOSE
  • OVEREXPRESSION
  • TRANSLOCATION
  • METABOLISM
  • CD36
  • ACIDIFICATION

Cite this