Atypical cognitive profile in patients with depression after myocardial infarction.

J.B. Dijkstra, J.J.M.H. Strik, R. Lousberg, J.H.H.J. Prickaerts*, W.J. Riedel, J. Jolles, H.M. van Praag, A. Honig

*Corresponding author for this work

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Background: We evaluated the cognitive profile of 48 patients with major depression following their first myocardial infarction (MI). Methods: The cognitive performance of the patients was compared with the performance of 48 nondepressed MI patients and 48 healthy controls. Results: Depressed MI patients performed slower on a simple cognitive speed related measure compared with non-depressed MI patients and healthy controls. Attention and speed-related aspects of cognitive functioning were not affected. Surprisingly, (depressed) MI patients showed even better performances with respect to memory function. Limitation: No patients with non-MI-related depression were included. Conclusions: The cognitive profile of major depression after MI differs from that of non-cardiac-related depressive disorder, as described in the literature. This may reflect a different etiology of post MI depression from non-cardiac-related depression.
Original languageEnglish
Pages (from-to)181-190
JournalJournal of Affective Disorders
Publication statusPublished - 1 Jan 2002

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