Background: We evaluated the cognitive profile of 48 patients with major depression following their first myocardial infarction (MI). Methods: The cognitive performance of the patients was compared with the performance of 48 nondepressed MI patients and 48 healthy controls. Results: Depressed MI patients performed slower on a simple cognitive speed related measure compared with non-depressed MI patients and healthy controls. Attention and speed-related aspects of cognitive functioning were not affected. Surprisingly, (depressed) MI patients showed even better performances with respect to memory function. Limitation: No patients with non-MI-related depression were included. Conclusions: The cognitive profile of major depression after MI differs from that of non-cardiac-related depressive disorder, as described in the literature. This may reflect a different etiology of post MI depression from non-cardiac-related depression.
Dijkstra, J. B., Strik, J. J. M. H., Lousberg, R., Prickaerts, J. H. H. J., Riedel, W. J., Jolles, J., van Praag, H. M., & Honig, A. (2002). Atypical cognitive profile in patients with depression after myocardial infarction. Journal of Affective Disorders, 20, 181-190. https://doi.org/10.1016/S0165-0327(01)00348-2