Attenuated palmitoylation of serotonin receptor 5-HT1A affects receptor function and contributes to depression-like behaviors

Nataliya Gorinski, Monika Bijata, Sonal Prasad, Alexander Wirth, Dalia Abdel Galil, Andre Zeug, Darla Bazovkina, Elena Kondaurova, Elizabeth Kulikova, Tatiana Ilchibaeva, Monika Zareba-Koziol, Francesco Papaleo, Diego Scheggia, Gaga Kochlamazashvili, Alexander Dityatev, Ian Smyth, Adam Krzystyniak, Jakub Wlodarczyk, Diethelm W. Richter, Tatyana StrekalovaStephan Sigrist, Claudia Bang, Lisa Hobuss, Jan Fiedler, Thomas Thum, Vladimir S. Naumenko, Ghanshyam Pandey, Evgeni Ponimaskin

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number3924
Number of pages14
JournalNature Communications
Volume10
DOIs
Publication statusPublished - 2 Sep 2019

Keywords

  • PREFRONTAL CORTEX
  • MAJOR DEPRESSION
  • 5-HYDROXYTRYPTAMINE(1A) RECEPTOR
  • PROTEIN PALMITOYLATION
  • CODING REGION
  • MICE LACKING
  • 1A BINDING
  • STRESS
  • EXPRESSION
  • MICRORNAS

Cite this

Gorinski, N., Bijata, M., Prasad, S., Wirth, A., Galil, D. A., Zeug, A., Bazovkina, D., Kondaurova, E., Kulikova, E., Ilchibaeva, T., Zareba-Koziol, M., Papaleo, F., Scheggia, D., Kochlamazashvili, G., Dityatev, A., Smyth, I., Krzystyniak, A., Wlodarczyk, J., Richter, D. W., ... Ponimaskin, E. (2019). Attenuated palmitoylation of serotonin receptor 5-HT1A affects receptor function and contributes to depression-like behaviors. Nature Communications, 10, [3924]. https://doi.org/10.1038/s41467-019-11876-5