Associations between unprocessed red and processed meat, poultry, seafood and egg intake and the risk of prostate cancer: A pooled analysis of 15 prospective cohort studies

Kana Wu; Donna Spiegelman; Tao Hou; Demetrius Albanes; Naomi E. Allen; Sonja I. Berndt; Piet A. van den Brandt; Graham G. Giles; Edward Giovannucci; R. Alexandra Goldbohm; Gary G. Goodman; Phyllis J. Goodman; Niclas Hakansson; Manami Inoue; Timothy J. Key; Laurence N. Kolonel; Satu Mannisto; Marjorie L. McCullough; Marian L. Neuhouser; Yikyung Park; Elizabeth A. Platz; Jeannette M. Schenk; Rashmi Sinha; Meir J. Stampfer; Victoria L. Stevens; Shoichiro Tsugane; Kala Visvanathan; Lynne R. Wilkens; Alicja Wolk; Regina G. Ziegler; Stephanie A. Smith-Warner

doi:10.1002/ijc.29973

Associations between unprocessed red and processed meat, poultry, seafood and egg intake and the risk of prostate cancer: A pooled analysis of 15 prospective cohort studies

Kana Wu^*
, Donna Spiegelman
, Tao Hou
, Demetrius Albanes
, Naomi E. Allen
, Sonja I. Berndt
, Piet A. van den Brandt
, Graham G. Giles
, Edward Giovannucci
, R. Alexandra Goldbohm
, Gary G. Goodman
, Phyllis J. Goodman
, Niclas Hakansson
, Manami Inoue
, Timothy J. Key
, Laurence N. Kolonel
, Satu Mannisto
, Marjorie L. McCullough
, Marian L. Neuhouser
, Yikyung Park

Elizabeth A. Platz, Jeannette M. Schenk, Rashmi Sinha, Meir J. Stampfer, Victoria L. Stevens, Shoichiro Tsugane, Kala Visvanathan, Lynne R. Wilkens, Alicja Wolk, Regina G. Ziegler, Stephanie A. Smith-Warner

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Reports relating meat intake to prostate cancer risk are inconsistent. Associations between these dietary factors and prostate cancer were examined in a consortium of 15 cohort studies. During follow-up, 52,683 incident prostate cancer cases, including 4,924 advanced cases, were identified among 842,149 men. Cox proportional hazard models were used to calculate study-specific relative risks (RR) and then pooled using random effects models. Results do not support a substantial effect of total red, unprocessed red and processed meat for all prostate cancer outcomes, except for a modest positive association for tumors identified as advanced stage at diagnosis (advanced(r)). For seafood, no substantial effect was observed for prostate cancer regardless of stage or grade. Poultry intake was inversely associated with risk of advanced and fatal cancers (pooled multivariable RR [MVRR], 95% confidence interval, comparing 45 vs.

Original language	English
Pages (from-to)	2368-2382
Number of pages	15
Journal	International Journal of Cancer
Volume	138
Issue number	10
DOIs	https://doi.org/10.1002/ijc.29973
Publication status	Published - 15 May 2016

Keywords

prostate cancer
diet
unprocessed red meat
processed meat
poultry
seafood
egg

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10.1002/ijc.29973

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Wu, K., Spiegelman, D., Hou, T., Albanes, D., Allen, N. E., Berndt, S. I., van den Brandt, P. A., Giles, G. G., Giovannucci, E., Goldbohm, R. A., Goodman, G. G., Goodman, P. J., Hakansson, N., Inoue, M., Key, T. J., Kolonel, L. N., Mannisto, S., McCullough, M. L., Neuhouser, M. L., ... Smith-Warner, S. A. (2016). Associations between unprocessed red and processed meat, poultry, seafood and egg intake and the risk of prostate cancer: A pooled analysis of 15 prospective cohort studies. International Journal of Cancer, 138(10), 2368-2382. https://doi.org/10.1002/ijc.29973

@article{fcd3aef5d767431480b417cd2d026b88,

title = "Associations between unprocessed red and processed meat, poultry, seafood and egg intake and the risk of prostate cancer: A pooled analysis of 15 prospective cohort studies",

abstract = "Reports relating meat intake to prostate cancer risk are inconsistent. Associations between these dietary factors and prostate cancer were examined in a consortium of 15 cohort studies. During follow-up, 52,683 incident prostate cancer cases, including 4,924 advanced cases, were identified among 842,149 men. Cox proportional hazard models were used to calculate study-specific relative risks (RR) and then pooled using random effects models. Results do not support a substantial effect of total red, unprocessed red and processed meat for all prostate cancer outcomes, except for a modest positive association for tumors identified as advanced stage at diagnosis (advanced(r)). For seafood, no substantial effect was observed for prostate cancer regardless of stage or grade. Poultry intake was inversely associated with risk of advanced and fatal cancers (pooled multivariable RR [MVRR], 95\% confidence interval, comparing 45 vs. ",

keywords = "prostate cancer, diet, unprocessed red meat, processed meat, poultry, seafood, egg",

author = "Kana Wu and Donna Spiegelman and Tao Hou and Demetrius Albanes and Allen, \{Naomi E.\} and Berndt, \{Sonja I.\} and \{van den Brandt\}, \{Piet A.\} and Giles, \{Graham G.\} and Edward Giovannucci and Goldbohm, \{R. Alexandra\} and Goodman, \{Gary G.\} and Goodman, \{Phyllis J.\} and Niclas Hakansson and Manami Inoue and Key, \{Timothy J.\} and Kolonel, \{Laurence N.\} and Satu Mannisto and McCullough, \{Marjorie L.\} and Neuhouser, \{Marian L.\} and Yikyung Park and Platz, \{Elizabeth A.\} and Schenk, \{Jeannette M.\} and Rashmi Sinha and Stampfer, \{Meir J.\} and Stevens, \{Victoria L.\} and Shoichiro Tsugane and Kala Visvanathan and Wilkens, \{Lynne R.\} and Alicja Wolk and Ziegler, \{Regina G.\} and Smith-Warner, \{Stephanie A.\}",

year = "2016",

month = may,

day = "15",

doi = "10.1002/ijc.29973",

language = "English",

volume = "138",

pages = "2368--2382",

journal = "International Journal of Cancer",

issn = "0020-7136",

publisher = "John Wiley \& Sons Inc.",

number = "10",

}

Wu, K, Spiegelman, D, Hou, T, Albanes, D, Allen, NE, Berndt, SI, van den Brandt, PA, Giles, GG, Giovannucci, E, Goldbohm, RA, Goodman, GG, Goodman, PJ, Hakansson, N, Inoue, M, Key, TJ, Kolonel, LN, Mannisto, S, McCullough, ML, Neuhouser, ML, Park, Y, Platz, EA, Schenk, JM, Sinha, R, Stampfer, MJ, Stevens, VL, Tsugane, S, Visvanathan, K, Wilkens, LR, Wolk, A, Ziegler, RG & Smith-Warner, SA 2016, 'Associations between unprocessed red and processed meat, poultry, seafood and egg intake and the risk of prostate cancer: A pooled analysis of 15 prospective cohort studies', International Journal of Cancer, vol. 138, no. 10, pp. 2368-2382. https://doi.org/10.1002/ijc.29973

Associations between unprocessed red and processed meat, poultry, seafood and egg intake and the risk of prostate cancer: A pooled analysis of 15 prospective cohort studies. / Wu, Kana; Spiegelman, Donna; Hou, Tao et al.
In: International Journal of Cancer, Vol. 138, No. 10, 15.05.2016, p. 2368-2382.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Associations between unprocessed red and processed meat, poultry, seafood and egg intake and the risk of prostate cancer: A pooled analysis of 15 prospective cohort studies

AU - Wu, Kana

AU - Spiegelman, Donna

AU - Hou, Tao

AU - Albanes, Demetrius

AU - Allen, Naomi E.

AU - Berndt, Sonja I.

AU - van den Brandt, Piet A.

AU - Giles, Graham G.

AU - Giovannucci, Edward

AU - Goldbohm, R. Alexandra

AU - Goodman, Gary G.

AU - Goodman, Phyllis J.

AU - Hakansson, Niclas

AU - Inoue, Manami

AU - Key, Timothy J.

AU - Kolonel, Laurence N.

AU - Mannisto, Satu

AU - McCullough, Marjorie L.

AU - Neuhouser, Marian L.

AU - Park, Yikyung

AU - Platz, Elizabeth A.

AU - Schenk, Jeannette M.

AU - Sinha, Rashmi

AU - Stampfer, Meir J.

AU - Stevens, Victoria L.

AU - Tsugane, Shoichiro

AU - Visvanathan, Kala

AU - Wilkens, Lynne R.

AU - Wolk, Alicja

AU - Ziegler, Regina G.

AU - Smith-Warner, Stephanie A.

PY - 2016/5/15

Y1 - 2016/5/15

N2 - Reports relating meat intake to prostate cancer risk are inconsistent. Associations between these dietary factors and prostate cancer were examined in a consortium of 15 cohort studies. During follow-up, 52,683 incident prostate cancer cases, including 4,924 advanced cases, were identified among 842,149 men. Cox proportional hazard models were used to calculate study-specific relative risks (RR) and then pooled using random effects models. Results do not support a substantial effect of total red, unprocessed red and processed meat for all prostate cancer outcomes, except for a modest positive association for tumors identified as advanced stage at diagnosis (advanced(r)). For seafood, no substantial effect was observed for prostate cancer regardless of stage or grade. Poultry intake was inversely associated with risk of advanced and fatal cancers (pooled multivariable RR [MVRR], 95% confidence interval, comparing 45 vs.

AB - Reports relating meat intake to prostate cancer risk are inconsistent. Associations between these dietary factors and prostate cancer were examined in a consortium of 15 cohort studies. During follow-up, 52,683 incident prostate cancer cases, including 4,924 advanced cases, were identified among 842,149 men. Cox proportional hazard models were used to calculate study-specific relative risks (RR) and then pooled using random effects models. Results do not support a substantial effect of total red, unprocessed red and processed meat for all prostate cancer outcomes, except for a modest positive association for tumors identified as advanced stage at diagnosis (advanced(r)). For seafood, no substantial effect was observed for prostate cancer regardless of stage or grade. Poultry intake was inversely associated with risk of advanced and fatal cancers (pooled multivariable RR [MVRR], 95% confidence interval, comparing 45 vs.

KW - prostate cancer

KW - diet

KW - unprocessed red meat

KW - processed meat

KW - poultry

KW - seafood

KW - egg

U2 - 10.1002/ijc.29973

DO - 10.1002/ijc.29973

M3 - Article

C2 - 26685908

SN - 0020-7136

VL - 138

SP - 2368

EP - 2382

JO - International Journal of Cancer

JF - International Journal of Cancer

IS - 10

ER -

Associations between unprocessed red and processed meat, poultry, seafood and egg intake and the risk of prostate cancer: A pooled analysis of 15 prospective cohort studies

Abstract

Keywords

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