Associations between unprocessed red and processed meat, poultry, seafood and egg intake and the risk of prostate cancer: A pooled analysis of 15 prospective cohort studies

Kana Wu*, Donna Spiegelman, Tao Hou, Demetrius Albanes, Naomi E. Allen, Sonja I. Berndt, Piet A. van den Brandt, Graham G. Giles, Edward Giovannucci, R. Alexandra Goldbohm, Gary G. Goodman, Phyllis J. Goodman, Niclas Hakansson, Manami Inoue, Timothy J. Key, Laurence N. Kolonel, Satu Mannisto, Marjorie L. McCullough, Marian L. Neuhouser, Yikyung ParkElizabeth A. Platz, Jeannette M. Schenk, Rashmi Sinha, Meir J. Stampfer, Victoria L. Stevens, Shoichiro Tsugane, Kala Visvanathan, Lynne R. Wilkens, Alicja Wolk, Regina G. Ziegler, Stephanie A. Smith-Warner

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Reports relating meat intake to prostate cancer risk are inconsistent. Associations between these dietary factors and prostate cancer were examined in a consortium of 15 cohort studies. During follow-up, 52,683 incident prostate cancer cases, including 4,924 advanced cases, were identified among 842,149 men. Cox proportional hazard models were used to calculate study-specific relative risks (RR) and then pooled using random effects models. Results do not support a substantial effect of total red, unprocessed red and processed meat for all prostate cancer outcomes, except for a modest positive association for tumors identified as advanced stage at diagnosis (advanced(r)). For seafood, no substantial effect was observed for prostate cancer regardless of stage or grade. Poultry intake was inversely associated with risk of advanced and fatal cancers (pooled multivariable RR [MVRR], 95% confidence interval, comparing 45 vs.
Original languageEnglish
Pages (from-to)2368-2382
JournalInternational Journal of Cancer
Issue number10
Publication statusPublished - 15 May 2016


  • prostate cancer
  • diet
  • unprocessed red meat
  • processed meat
  • poultry
  • seafood
  • egg

Cite this