Abstract
This systematic review evaluated which outcome variables and cut-off values of pretreatment exercise tests are associated with treatment complications in patients with stage I-III non-small cell lung cancer (NSCLC). PRISMA and Cochrane guidelines were followed. A total of 38 studies with adult patients undergoing treatment for stage I-III NSCLC who completed pretreatment exercise tests, and of whom treatment-related complications were recorded were included. A lower oxygen uptake at peak exercise amongst several other variables on the cardiopulmonary exercise test and a lower performance on field tests, such as the incremental shuttle walk test, stair-climb test, and 6-minute walk test, were associated with a higher risk for postoperative complications and/ or postoperative mortality. Cut-off values were reported in a limited number of studies and were inconsistent. Due to the variety in outcomes, further research is needed to evaluate which outcomes and cut-off values of physical exercise tests are most clinically relevant.
Original language | English |
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Number of pages | 13 |
Journal | Critical Reviews in Oncology/Hematology |
Volume | 158 |
DOIs | |
Publication status | Published - 1 Feb 2021 |
Keywords
- Aerobic capacity
- Lung cancer
- Perioperative care
- Prehabilitation
- Preoperative risk assessment
- SURGERY
- OXYGEN-CONSUMPTION
- 6-MIN WALK
- WALK TEST
- HOSPITAL STAY
- RESECTION
- EXERCISE CAPACITY
- OBSTRUCTIVE PULMONARY-DISEASE
- POSTOPERATIVE COMPLICATIONS
- INCREASED RISK