Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis

J. William L. Brown; Alasdair Coles; Dana Horakova; Eva Havrdova; Guillermo Izquierdo; Alexandre Prat; Marc Girard; Pierre Duquette; Maria Trojano; Alessandra Lugaresi; Roberto Bergamaschi; Pierre Grammond; Raed Alroughani; Raymond Hupperts; Pamela McCombe; Vincent Van Pesch; Patrizia Sola; Diana Ferraro; Francois Grand'Maison; Murat Terzi; Jeannette Lechner-Scott; Schlomo Flechter; Mark Slee; Vahid Shaygannejad; Eugenio Pucci; Franco Granella; Vilija Jokubaitis; Mark Willis; Claire Rice; Neil Scolding; Alastair Wilkins; Owen R. Pearson; Tjalf Ziemssen; Michael Hutchinson; Katharine Harding; Joanne Jones; Christopher McGuigan; Helmut Butzkueven; Tomas Kalincik; Neil Robertson; Marco Onofrj; Giovanna De Luca; Valeria Di Tommaso; Daniela Travaglini; Erika Pietrolongo; Maria di Ioia; Deborah Farina; Luca Mancinelli; Suzanne Hodgkinson; Celia Oreja-Guevara; MSBase Study Grp

doi:10.1001/jama.2018.20588

Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis

J. William L. Brown, Alasdair Coles, Dana Horakova, Eva Havrdova, Guillermo Izquierdo, Alexandre Prat, Marc Girard, Pierre Duquette, Maria Trojano, Alessandra Lugaresi, Roberto Bergamaschi, Pierre Grammond, Raed Alroughani, Raymond Hupperts, Pamela McCombe, Vincent Van Pesch, Patrizia Sola, Diana Ferraro, Francois Grand'Maison, Murat TerziJeannette Lechner-Scott, Schlomo Flechter, Mark Slee, Vahid Shaygannejad, Eugenio Pucci, Franco Granella, Vilija Jokubaitis, Mark Willis, Claire Rice, Neil Scolding, Alastair Wilkins, Owen R. Pearson, Tjalf Ziemssen, Michael Hutchinson, Katharine Harding, Joanne Jones, Christopher McGuigan, Helmut Butzkueven, Tomas Kalincik^*, Neil Robertson, Marco Onofrj, Giovanna De Luca, Valeria Di Tommaso, Daniela Travaglini, Erika Pietrolongo, Maria di Ioia, Deborah Farina, Luca Mancinelli, Suzanne Hodgkinson, Celia Oreja-Guevara, MSBase Study Grp

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	175-187
Number of pages	13
Journal	JAMA-Journal of the American Medical Association
Volume	321
Issue number	2
DOIs	https://doi.org/10.1001/jama.2018.20588
Publication status	Published - 15 Jan 2019

Keywords

INTERFERON-BETA
GLATIRAMER ACETATE
ALEMTUZUMAB
NATALIZUMAB
FINGOLIMOD
DISABILITY
MULTICENTER
OUTCOMES
TIME

Access to Document

10.1001/jama.2018.20588

Cite this

Brown, J. W. L., Coles, A., Horakova, D., Havrdova, E., Izquierdo, G., Prat, A., Girard, M., Duquette, P., Trojano, M., Lugaresi, A., Bergamaschi, R., Grammond, P., Alroughani, R., Hupperts, R., McCombe, P., Van Pesch, V., Sola, P., Ferraro, D., Grand'Maison, F., ... MSBase Study Grp (2019). Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis. JAMA-Journal of the American Medical Association, 321(2), 175-187. https://doi.org/10.1001/jama.2018.20588

Brown, J. William L. ; Coles, Alasdair ; Horakova, Dana ; Havrdova, Eva ; Izquierdo, Guillermo ; Prat, Alexandre ; Girard, Marc ; Duquette, Pierre ; Trojano, Maria ; Lugaresi, Alessandra ; Bergamaschi, Roberto ; Grammond, Pierre ; Alroughani, Raed ; Hupperts, Raymond ; McCombe, Pamela ; Van Pesch, Vincent ; Sola, Patrizia ; Ferraro, Diana ; Grand'Maison, Francois ; Terzi, Murat ; Lechner-Scott, Jeannette ; Flechter, Schlomo ; Slee, Mark ; Shaygannejad, Vahid ; Pucci, Eugenio ; Granella, Franco ; Jokubaitis, Vilija ; Willis, Mark ; Rice, Claire ; Scolding, Neil ; Wilkins, Alastair ; Pearson, Owen R. ; Ziemssen, Tjalf ; Hutchinson, Michael ; Harding, Katharine ; Jones, Joanne ; McGuigan, Christopher ; Butzkueven, Helmut ; Kalincik, Tomas ; Robertson, Neil ; Onofrj, Marco ; De Luca, Giovanna ; Di Tommaso, Valeria ; Travaglini, Daniela ; Pietrolongo, Erika ; di Ioia, Maria ; Farina, Deborah ; Mancinelli, Luca ; Hodgkinson, Suzanne ; Oreja-Guevara, Celia ; MSBase Study Grp. / Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis. In: JAMA-Journal of the American Medical Association. 2019 ; Vol. 321, No. 2. pp. 175-187.

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title = "Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis",

keywords = "INTERFERON-BETA, GLATIRAMER ACETATE, ALEMTUZUMAB, NATALIZUMAB, FINGOLIMOD, DISABILITY, MULTICENTER, OUTCOMES, TIME",

author = "Brown, {J. William L.} and Alasdair Coles and Dana Horakova and Eva Havrdova and Guillermo Izquierdo and Alexandre Prat and Marc Girard and Pierre Duquette and Maria Trojano and Alessandra Lugaresi and Roberto Bergamaschi and Pierre Grammond and Raed Alroughani and Raymond Hupperts and Pamela McCombe and {Van Pesch}, Vincent and Patrizia Sola and Diana Ferraro and Francois Grand'Maison and Murat Terzi and Jeannette Lechner-Scott and Schlomo Flechter and Mark Slee and Vahid Shaygannejad and Eugenio Pucci and Franco Granella and Vilija Jokubaitis and Mark Willis and Claire Rice and Neil Scolding and Alastair Wilkins and Pearson, {Owen R.} and Tjalf Ziemssen and Michael Hutchinson and Katharine Harding and Joanne Jones and Christopher McGuigan and Helmut Butzkueven and Tomas Kalincik and Neil Robertson and Marco Onofrj and {De Luca}, Giovanna and {Di Tommaso}, Valeria and Daniela Travaglini and Erika Pietrolongo and {di Ioia}, Maria and Deborah Farina and Luca Mancinelli and Suzanne Hodgkinson and Celia Oreja-Guevara and {MSBase Study Grp}",

year = "2019",

month = jan,

day = "15",

doi = "10.1001/jama.2018.20588",

language = "English",

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Brown, JWL, Coles, A, Horakova, D, Havrdova, E, Izquierdo, G, Prat, A, Girard, M, Duquette, P, Trojano, M, Lugaresi, A, Bergamaschi, R, Grammond, P, Alroughani, R, Hupperts, R, McCombe, P, Van Pesch, V, Sola, P, Ferraro, D, Grand'Maison, F, Terzi, M, Lechner-Scott, J, Flechter, S, Slee, M, Shaygannejad, V, Pucci, E, Granella, F, Jokubaitis, V, Willis, M, Rice, C, Scolding, N, Wilkins, A, Pearson, OR, Ziemssen, T, Hutchinson, M, Harding, K, Jones, J, McGuigan, C, Butzkueven, H, Kalincik, T, Robertson, N, Onofrj, M, De Luca, G, Di Tommaso, V, Travaglini, D, Pietrolongo, E, di Ioia, M, Farina, D, Mancinelli, L, Hodgkinson, S, Oreja-Guevara, C & MSBase Study Grp 2019, 'Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis', JAMA-Journal of the American Medical Association, vol. 321, no. 2, pp. 175-187. https://doi.org/10.1001/jama.2018.20588

Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis. / Brown, J. William L.; Coles, Alasdair; Horakova, Dana; Havrdova, Eva; Izquierdo, Guillermo; Prat, Alexandre; Girard, Marc; Duquette, Pierre; Trojano, Maria; Lugaresi, Alessandra; Bergamaschi, Roberto; Grammond, Pierre; Alroughani, Raed; Hupperts, Raymond; McCombe, Pamela; Van Pesch, Vincent; Sola, Patrizia; Ferraro, Diana; Grand'Maison, Francois; Terzi, Murat; Lechner-Scott, Jeannette; Flechter, Schlomo; Slee, Mark; Shaygannejad, Vahid; Pucci, Eugenio; Granella, Franco; Jokubaitis, Vilija; Willis, Mark; Rice, Claire; Scolding, Neil; Wilkins, Alastair; Pearson, Owen R.; Ziemssen, Tjalf; Hutchinson, Michael; Harding, Katharine; Jones, Joanne; McGuigan, Christopher; Butzkueven, Helmut; Kalincik, Tomas; Robertson, Neil; Onofrj, Marco; De Luca, Giovanna; Di Tommaso, Valeria; Travaglini, Daniela; Pietrolongo, Erika; di Ioia, Maria; Farina, Deborah; Mancinelli, Luca; Hodgkinson, Suzanne; Oreja-Guevara, Celia; MSBase Study Grp.

In: JAMA-Journal of the American Medical Association, Vol. 321, No. 2, 15.01.2019, p. 175-187.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis

AU - Brown, J. William L.

AU - Coles, Alasdair

AU - Horakova, Dana

AU - Havrdova, Eva

AU - Izquierdo, Guillermo

AU - Prat, Alexandre

AU - Girard, Marc

AU - Duquette, Pierre

AU - Trojano, Maria

AU - Lugaresi, Alessandra

AU - Bergamaschi, Roberto

AU - Grammond, Pierre

AU - Alroughani, Raed

AU - Hupperts, Raymond

AU - McCombe, Pamela

AU - Van Pesch, Vincent

AU - Sola, Patrizia

AU - Ferraro, Diana

AU - Grand'Maison, Francois

AU - Terzi, Murat

AU - Lechner-Scott, Jeannette

AU - Flechter, Schlomo

AU - Slee, Mark

AU - Shaygannejad, Vahid

AU - Pucci, Eugenio

AU - Granella, Franco

AU - Jokubaitis, Vilija

AU - Willis, Mark

AU - Rice, Claire

AU - Scolding, Neil

AU - Wilkins, Alastair

AU - Pearson, Owen R.

AU - Ziemssen, Tjalf

AU - Hutchinson, Michael

AU - Harding, Katharine

AU - Jones, Joanne

AU - McGuigan, Christopher

AU - Butzkueven, Helmut

AU - Kalincik, Tomas

AU - Robertson, Neil

AU - Onofrj, Marco

AU - De Luca, Giovanna

AU - Di Tommaso, Valeria

AU - Travaglini, Daniela

AU - Pietrolongo, Erika

AU - di Ioia, Maria

AU - Farina, Deborah

AU - Mancinelli, Luca

AU - Hodgkinson, Suzanne

AU - Oreja-Guevara, Celia

AU - MSBase Study Grp

PY - 2019/1/15

Y1 - 2019/1/15

KW - INTERFERON-BETA

KW - GLATIRAMER ACETATE

KW - ALEMTUZUMAB

KW - NATALIZUMAB

KW - FINGOLIMOD

KW - DISABILITY

KW - MULTICENTER

KW - OUTCOMES

KW - TIME

U2 - 10.1001/jama.2018.20588

DO - 10.1001/jama.2018.20588

M3 - Article

VL - 321

SP - 175

EP - 187

JO - JAMA-Journal of the American Medical Association

JF - JAMA-Journal of the American Medical Association

SN - 0098-7484

IS - 2

ER -