Abstract
Introduction: In a previous meta-analysis, we derived pooled estimates for the association of left ventricular mass (LVM) and hypertrophy (LVH), as diagnosed by electrocardiography or echocardiography, with the ACE D/I polymorphism. We updated this meta-analysis until May 2009 only considering echocardiographic phenotypes. Methods: We computed pooled estimates from a random-effects model. Results: Across 38 studies, both DD homozygotes (n = 2440) and DI heterozygotes (n = 4310) had higher (p
Original language | English |
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Pages (from-to) | 243-253 |
Journal | Journal of the Renin-angiotensin-aldosterone System |
Volume | 12 |
Issue number | 3 |
DOIs | |
Publication status | Published - Sept 2011 |
Keywords
- ACE
- echocardiography
- left ventricular geometry
- left ventricular mass
- meta-analysis