Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease

, Stefan L. C. Geijselaers, Pauline Aalten, Inez H. G. B. Ramakers, Peter Paul De Deyn, Annemieke C. Heijboer, Huiberdina L. Koek, Marcel G. M. OldeRikkert, Janne M. Papma, Fransje E. Reesink, Lieke L. Smits, Coen D. A. Stehouwer, Charlotte E. Teunissen, Frans R. J. Verhey, Wiesje M. van der Flier, Geert Jan Biessels

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)309-320
Number of pages12
JournalJournal of Alzheimer's Disease
Volume61
Issue number1
DOIs
Publication statusPublished - 1 Jan 2018

Keywords

  • Alzheimer's disease
  • cerebrospinal fluid
  • cognition
  • epidemiology
  • insulin
  • IMPAIRED OLDER-ADULTS
  • INTRANASAL INSULIN
  • GLUCOSE-METABOLISM
  • DIFFERENTIAL SENSITIVITY
  • RESISTANCE SYNDROME
  • IMPROVES COGNITION
  • APOE GENOTYPE
  • TAU-PROTEIN
  • MEMORY
  • BRAIN
  • Humans
  • Middle Aged
  • Male
  • tau Proteins/cerebrospinal fluid
  • Cognition Disorders/diagnosis
  • Apolipoprotein E4/genetics
  • Mental Status Schedule
  • Female
  • Signal Transduction/genetics
  • Insulin/cerebrospinal fluid
  • Peptide Fragments/cerebrospinal fluid
  • Amyloid beta-Peptides/cerebrospinal fluid
  • Neuropsychological Tests
  • Alzheimer Disease/cerebrospinal fluid
  • Aged
  • Brain/metabolism
  • RISK
  • IMPAIRED INSULIN

Cite this

Geijselaers, Stefan L. C. ; Aalten, Pauline ; Ramakers, Inez H. G. B. ; De Deyn, Peter Paul ; Heijboer, Annemieke C. ; Koek, Huiberdina L. ; OldeRikkert, Marcel G. M. ; Papma, Janne M. ; Reesink, Fransje E. ; Smits, Lieke L. ; Stehouwer, Coen D. A. ; Teunissen, Charlotte E. ; Verhey, Frans R. J. ; van der Flier, Wiesje M. ; Biessels, Geert Jan. / Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease. In: Journal of Alzheimer's Disease. 2018 ; Vol. 61, No. 1. pp. 309-320.
@article{685166e94b924037b520bdc3023ea29a,
title = "Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease",
keywords = "Alzheimer's disease, cerebrospinal fluid, cognition, epidemiology, insulin, IMPAIRED OLDER-ADULTS, INTRANASAL INSULIN, GLUCOSE-METABOLISM, DIFFERENTIAL SENSITIVITY, RESISTANCE SYNDROME, IMPROVES COGNITION, APOE GENOTYPE, TAU-PROTEIN, MEMORY, BRAIN, Humans, Middle Aged, Male, tau Proteins/cerebrospinal fluid, Cognition Disorders/diagnosis, Apolipoprotein E4/genetics, Mental Status Schedule, Female, Signal Transduction/genetics, Insulin/cerebrospinal fluid, Peptide Fragments/cerebrospinal fluid, Amyloid beta-Peptides/cerebrospinal fluid, Neuropsychological Tests, Alzheimer Disease/cerebrospinal fluid, Aged, Brain/metabolism, RISK, IMPAIRED INSULIN",
author = "Geijselaers, {Stefan L. C.} and Pauline Aalten and Ramakers, {Inez H. G. B.} and {De Deyn}, {Peter Paul} and Heijboer, {Annemieke C.} and Koek, {Huiberdina L.} and OldeRikkert, {Marcel G. M.} and Papma, {Janne M.} and Reesink, {Fransje E.} and Smits, {Lieke L.} and Stehouwer, {Coen D. A.} and Teunissen, {Charlotte E.} and Verhey, {Frans R. J.} and {van der Flier}, {Wiesje M.} and Biessels, {Geert Jan}",
year = "2018",
month = "1",
day = "1",
doi = "10.3233/JAD-170522",
language = "English",
volume = "61",
pages = "309--320",
journal = "Journal of Alzheimer's Disease",
issn = "1387-2877",
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number = "1",

}

Geijselaers, SLC, Aalten, P, Ramakers, IHGB, De Deyn, PP, Heijboer, AC, Koek, HL, OldeRikkert, MGM, Papma, JM, Reesink, FE, Smits, LL, Stehouwer, CDA, Teunissen, CE, Verhey, FRJ & van der Flier, WM & Biessels, GJ 2018, 'Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease', Journal of Alzheimer's Disease, vol. 61, no. 1, pp. 309-320. https://doi.org/10.3233/JAD-170522

Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease. /; Geijselaers, Stefan L. C.; Aalten, Pauline; Ramakers, Inez H. G. B.; De Deyn, Peter Paul; Heijboer, Annemieke C.; Koek, Huiberdina L.; OldeRikkert, Marcel G. M.; Papma, Janne M.; Reesink, Fransje E.; Smits, Lieke L.; Stehouwer, Coen D. A.; Teunissen, Charlotte E.; Verhey, Frans R. J.; van der Flier, Wiesje M.; Biessels, Geert Jan.

In: Journal of Alzheimer's Disease, Vol. 61, No. 1, 01.01.2018, p. 309-320.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease

AU - Geijselaers, Stefan L. C.

AU - Aalten, Pauline

AU - Ramakers, Inez H. G. B.

AU - De Deyn, Peter Paul

AU - Heijboer, Annemieke C.

AU - Koek, Huiberdina L.

AU - OldeRikkert, Marcel G. M.

AU - Papma, Janne M.

AU - Reesink, Fransje E.

AU - Smits, Lieke L.

AU - Stehouwer, Coen D. A.

AU - Teunissen, Charlotte E.

AU - Verhey, Frans R. J.

AU - van der Flier, Wiesje M.

AU - Biessels, Geert Jan

PY - 2018/1/1

Y1 - 2018/1/1

KW - Alzheimer's disease

KW - cerebrospinal fluid

KW - cognition

KW - epidemiology

KW - insulin

KW - IMPAIRED OLDER-ADULTS

KW - INTRANASAL INSULIN

KW - GLUCOSE-METABOLISM

KW - DIFFERENTIAL SENSITIVITY

KW - RESISTANCE SYNDROME

KW - IMPROVES COGNITION

KW - APOE GENOTYPE

KW - TAU-PROTEIN

KW - MEMORY

KW - BRAIN

KW - Humans

KW - Middle Aged

KW - Male

KW - tau Proteins/cerebrospinal fluid

KW - Cognition Disorders/diagnosis

KW - Apolipoprotein E4/genetics

KW - Mental Status Schedule

KW - Female

KW - Signal Transduction/genetics

KW - Insulin/cerebrospinal fluid

KW - Peptide Fragments/cerebrospinal fluid

KW - Amyloid beta-Peptides/cerebrospinal fluid

KW - Neuropsychological Tests

KW - Alzheimer Disease/cerebrospinal fluid

KW - Aged

KW - Brain/metabolism

KW - RISK

KW - IMPAIRED INSULIN

U2 - 10.3233/JAD-170522

DO - 10.3233/JAD-170522

M3 - Article

VL - 61

SP - 309

EP - 320

JO - Journal of Alzheimer's Disease

JF - Journal of Alzheimer's Disease

SN - 1387-2877

IS - 1

ER -