Assessment of the scientific rigour of randomized controlled trials on the effectiveness of cognitive behavioural therapy and graded exercise therapy for patients with myalgic encephalomyelitis/chronic fatigue syndrome: A systematic review

S.A. Ahmed*, J.C. Mewes, H.J.M. Vrijhoef

*Corresponding author for this work

Research output: Contribution to journal(Systematic) Review article peer-review

Abstract

Cognitive behavioural therapy and graded exercise therapy have been promoted as effective treatments for patients with myalgic encephalomyelitis/chronic fatigue syndrome. However, criticism on the scientific rigour of these studies has been raised. This review assessed the methodological quality of studies on the effectiveness of cognitive behavioural therapy and graded exercise therapy. The methodological quality of the 18 included studies was found to be relatively low, as bias was prominently found, affecting the main outcome measures of the studies (fatigue, physical functioning and functional impairment/status). Future research should focus on including more objective outcome measures in a well-defined patient population.
Original languageEnglish
Pages (from-to)240-255
Number of pages16
JournalJournal of Health Psychology
Volume25
Issue number2
DOIs
Publication statusPublished - 1 Feb 2020

Keywords

  • chronic fatigue syndrome
  • cognitive behavioural therapy
  • follow-up
  • graded exercise therapy
  • interventions
  • myalgic encephalomyelitis
  • systematic review
  • INTERVENTIONS
  • FOLLOW-UP

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