Assessing fitness to drive in patients with different types of dementia

Dafne Piersma, Anselm B. M. Fuermaier, Dick de Waard, Ragnhild J. Davidse, Jolieke de Groot, Michelle J A Doumen, Ruud A. Bredewoud, René Claesen, Afina W. Lemstra, Philip Scheltens, Annemiek Vermeeren, Rudolf Ponds, Frans Verhey, Peter P. De Deyn, Wiebo H. Brouwer, Oliver Tucha

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Dementia is a risk factor for unsafe driving. Therefore, an assessment strategy has recently been developed for the prediction of fitness to drive in patients with the Alzheimer disease (AD). The aim of this study was to investigate whether this strategy is also predictive of fitness to drive in patients with non-AD dementia, that is, vascular dementia, frontotemporal dementia, and dementia with Lewy bodies. Predictors were derived from 3 types of assessment: clinical interviews, neuropsychological tests, and driving simulator rides. The criterion was the pass-fail outcome of an official on-road driving assessment. About half of the patients with non-AD dementia (n=34) failed the on-road driving assessment. Neuropsychological assessment [area under the curve (AUC)=0.786] was significantly predictive of fitness to drive in patients with non-AD dementia, however, clinical interviews (AUC=0.559) and driving simulator rides (AUC=0.404) were not. The fitness-to-drive assessment strategy with the 3 types of assessment combined (AUC=0.635) was not found to significantly predict fitness to drive in non-AD dementia. Different types of dementia require different measures and assessment strategies.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/.

Original languageEnglish
Pages (from-to)70-75
Number of pages6
JournalAlzheimer Disease & Associated Disorders
Volume32
Issue number1
DOIs
Publication statusPublished - 1 Jan 2018

Keywords

  • Journal Article
  • dementia with Lewy bodies
  • COGNITIVE IMPAIRMENTS
  • car driving
  • vascular dementia
  • ABILITY
  • frontotemporal dementia
  • PEOPLE
  • fitness-to-drive assessment
  • FRONTOTEMPORAL LOBAR DEGENERATION
  • DIAGNOSTIC-CRITERIA

Cite this

Piersma, D., Fuermaier, A. B. M., de Waard, D., Davidse, R. J., de Groot, J., Doumen, M. J. A., ... Tucha, O. (2018). Assessing fitness to drive in patients with different types of dementia. Alzheimer Disease & Associated Disorders, 32(1), 70-75. https://doi.org/10.1097/WAD.0000000000000221
Piersma, Dafne ; Fuermaier, Anselm B. M. ; de Waard, Dick ; Davidse, Ragnhild J. ; de Groot, Jolieke ; Doumen, Michelle J A ; Bredewoud, Ruud A. ; Claesen, René ; Lemstra, Afina W. ; Scheltens, Philip ; Vermeeren, Annemiek ; Ponds, Rudolf ; Verhey, Frans ; De Deyn, Peter P. ; Brouwer, Wiebo H. ; Tucha, Oliver. / Assessing fitness to drive in patients with different types of dementia. In: Alzheimer Disease & Associated Disorders. 2018 ; Vol. 32, No. 1. pp. 70-75.
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abstract = "Dementia is a risk factor for unsafe driving. Therefore, an assessment strategy has recently been developed for the prediction of fitness to drive in patients with the Alzheimer disease (AD). The aim of this study was to investigate whether this strategy is also predictive of fitness to drive in patients with non-AD dementia, that is, vascular dementia, frontotemporal dementia, and dementia with Lewy bodies. Predictors were derived from 3 types of assessment: clinical interviews, neuropsychological tests, and driving simulator rides. The criterion was the pass-fail outcome of an official on-road driving assessment. About half of the patients with non-AD dementia (n=34) failed the on-road driving assessment. Neuropsychological assessment [area under the curve (AUC)=0.786] was significantly predictive of fitness to drive in patients with non-AD dementia, however, clinical interviews (AUC=0.559) and driving simulator rides (AUC=0.404) were not. The fitness-to-drive assessment strategy with the 3 types of assessment combined (AUC=0.635) was not found to significantly predict fitness to drive in non-AD dementia. Different types of dementia require different measures and assessment strategies.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/.",
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author = "Dafne Piersma and Fuermaier, {Anselm B. M.} and {de Waard}, Dick and Davidse, {Ragnhild J.} and {de Groot}, Jolieke and Doumen, {Michelle J A} and Bredewoud, {Ruud A.} and Ren{\'e} Claesen and Lemstra, {Afina W.} and Philip Scheltens and Annemiek Vermeeren and Rudolf Ponds and Frans Verhey and {De Deyn}, {Peter P.} and Brouwer, {Wiebo H.} and Oliver Tucha",
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Piersma, D, Fuermaier, ABM, de Waard, D, Davidse, RJ, de Groot, J, Doumen, MJA, Bredewoud, RA, Claesen, R, Lemstra, AW, Scheltens, P, Vermeeren, A, Ponds, R, Verhey, F, De Deyn, PP, Brouwer, WH & Tucha, O 2018, 'Assessing fitness to drive in patients with different types of dementia', Alzheimer Disease & Associated Disorders, vol. 32, no. 1, pp. 70-75. https://doi.org/10.1097/WAD.0000000000000221

Assessing fitness to drive in patients with different types of dementia. / Piersma, Dafne; Fuermaier, Anselm B. M.; de Waard, Dick; Davidse, Ragnhild J.; de Groot, Jolieke; Doumen, Michelle J A; Bredewoud, Ruud A.; Claesen, René; Lemstra, Afina W.; Scheltens, Philip; Vermeeren, Annemiek; Ponds, Rudolf; Verhey, Frans; De Deyn, Peter P.; Brouwer, Wiebo H.; Tucha, Oliver.

In: Alzheimer Disease & Associated Disorders, Vol. 32, No. 1, 01.01.2018, p. 70-75.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Fuermaier, Anselm B. M.

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AU - de Groot, Jolieke

AU - Doumen, Michelle J A

AU - Bredewoud, Ruud A.

AU - Claesen, René

AU - Lemstra, Afina W.

AU - Scheltens, Philip

AU - Vermeeren, Annemiek

AU - Ponds, Rudolf

AU - Verhey, Frans

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AU - Tucha, Oliver

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N2 - Dementia is a risk factor for unsafe driving. Therefore, an assessment strategy has recently been developed for the prediction of fitness to drive in patients with the Alzheimer disease (AD). The aim of this study was to investigate whether this strategy is also predictive of fitness to drive in patients with non-AD dementia, that is, vascular dementia, frontotemporal dementia, and dementia with Lewy bodies. Predictors were derived from 3 types of assessment: clinical interviews, neuropsychological tests, and driving simulator rides. The criterion was the pass-fail outcome of an official on-road driving assessment. About half of the patients with non-AD dementia (n=34) failed the on-road driving assessment. Neuropsychological assessment [area under the curve (AUC)=0.786] was significantly predictive of fitness to drive in patients with non-AD dementia, however, clinical interviews (AUC=0.559) and driving simulator rides (AUC=0.404) were not. The fitness-to-drive assessment strategy with the 3 types of assessment combined (AUC=0.635) was not found to significantly predict fitness to drive in non-AD dementia. Different types of dementia require different measures and assessment strategies.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/.

AB - Dementia is a risk factor for unsafe driving. Therefore, an assessment strategy has recently been developed for the prediction of fitness to drive in patients with the Alzheimer disease (AD). The aim of this study was to investigate whether this strategy is also predictive of fitness to drive in patients with non-AD dementia, that is, vascular dementia, frontotemporal dementia, and dementia with Lewy bodies. Predictors were derived from 3 types of assessment: clinical interviews, neuropsychological tests, and driving simulator rides. The criterion was the pass-fail outcome of an official on-road driving assessment. About half of the patients with non-AD dementia (n=34) failed the on-road driving assessment. Neuropsychological assessment [area under the curve (AUC)=0.786] was significantly predictive of fitness to drive in patients with non-AD dementia, however, clinical interviews (AUC=0.559) and driving simulator rides (AUC=0.404) were not. The fitness-to-drive assessment strategy with the 3 types of assessment combined (AUC=0.635) was not found to significantly predict fitness to drive in non-AD dementia. Different types of dementia require different measures and assessment strategies.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/.

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KW - COGNITIVE IMPAIRMENTS

KW - car driving

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KW - fitness-to-drive assessment

KW - FRONTOTEMPORAL LOBAR DEGENERATION

KW - DIAGNOSTIC-CRITERIA

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SN - 0893-0341

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Piersma D, Fuermaier ABM, de Waard D, Davidse RJ, de Groot J, Doumen MJA et al. Assessing fitness to drive in patients with different types of dementia. Alzheimer Disease & Associated Disorders. 2018 Jan 1;32(1):70-75. https://doi.org/10.1097/WAD.0000000000000221