Areas V1 and V2 show microsaccade-related 3-4-Hz covariation in gamma power and frequency

E Lowet, M J Roberts, C A Bosman, P Fries, P De Weerd

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Abstract

Neuronal gamma-band synchronization (25-80 Hz) in visual cortex appears sustained and stable during prolonged visual stimulation when investigated with conventional averages across trials. However, recent studies in macaque visual cortex have used single-trial analyses to show that both power and frequency of gamma oscillations exhibit substantial moment-by-moment variation. This has raised the question of whether these apparently random variations might limit the functional role of gamma-band synchronization for neural processing. Here, we studied the moment-by-moment variation in gamma oscillation power and frequency, as well as inter-areal gamma synchronization, by simultaneously recording local field potentials in V1 and V2 of two macaque monkeys. We additionally analyzed electrocorticographic V1 data from a third monkey. Our analyses confirm that gamma-band synchronization is not stationary and sustained but undergoes moment-by-moment variations in power and frequency. However, those variations are neither random and nor a possible obstacle to neural communication. Instead, the gamma power and frequency variations are highly structured, shared between areas and shaped by a microsaccade-related 3-4-Hz theta rhythm. Our findings provide experimental support for the suggestion that cross-frequency coupling might structure and facilitate the information flow between brain regions.

Original languageEnglish
Pages (from-to)1286-1296
Number of pages11
JournalEuropean Journal of Neuroscience
Volume43
Issue number10
DOIs
Publication statusPublished - May 2016

Keywords

  • electrophysiology
  • gamma-band response
  • monkey
  • saccade
  • visual system
  • PRIMARY VISUAL-CORTEX
  • NEURONAL OSCILLATIONS
  • BAND SYNCHRONIZATION
  • MACAQUE MONKEY
  • ALPHA-ACTIVITY
  • BRAIN SIGNALS
  • EYE-MOVEMENTS
  • ATTENTION
  • THETA
  • COHERENCE

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