Abstract
AIMS: Mapping and interpretation of wave conduction patterns recorded during simultaneous mapping of the electrical activity on both endocardial and epicardial surfaces are challenging because of the difficulty of reconstruction of reciprocal alignment of electrodes in space. Here, we suggest a method to overcome this difficulty using a concept of maximized endo-epicardial phase coherence.
METHODS AND RESULTS: Endo-epicardial mapping was performed in six humans during induced atrial fibrillation (AF) in right atria using two sets of 8 × 8 electrode plaques. For each electrode, mean phase coherence (MPC) with all electrodes on the opposite side of the atrial wall was calculated. Localization error was defined as a distance between the directly opposing electrode and the electrode with the maximal MPC. Overall, there was a linear correlation between MPC and distance between electrodes with R(2) = 0.34. Localization error obtained for electrodes of the plaque in six patients resulted in a mean 2.3 ± 1.9 mm for 25 s electrogram segment length. Eighty-four per cent of the measurements resulted in error smaller than 3.4 mm. The duration of the recording used to compute MPC was negatively correlated with localization error; however, the effect reached plateau for segment durations longer than 15 s.
CONCLUSION: Application of the concept of maximized endo-epicardial phase coherence to electrograms during AF allows reconstruction of reciprocal alignment of the electrodes on the opposite side of the atrial wall. This approach may be especially useful in settings where the spatial position of endo- and epicardial electrodes for intracardiac mapping cannot otherwise be determined.
Original language | English |
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Pages (from-to) | iv135-iv140 |
Journal | EP Europace |
Volume | 16 |
Issue number | Suppl 4 |
DOIs | |
Publication status | Published - Nov 2014 |
Keywords
- Action Potentials
- Atrial Fibrillation
- Computer Simulation
- Endocardium
- Epicardial Mapping
- Heart Conduction System
- Humans
- Models, Cardiovascular
- Pericardium
- Predictive Value of Tests
- Reproducibility of Results
- Signal Processing, Computer-Assisted
- Time Factors