Application of Medical Moisture Retention Cream (ALHYDRAN®), A New Option in the Treatment of Venous Eczema

A.A.L.M. Rondas*, Jos Schols

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Aim: Patients with venous eczema may suffer considerably from redness, crusts, pain, flaking and itching. Ingeneral, as treatment, compression therapy and indifferent ointments/crèmes are used, often together with topicalsteroids, though the latter may exhibit considerable side effects. This study aims to explore the effect of MedicalMoisture Retention Cream (MMRC = ALHYDRAN®) on the symptoms and complaints of patients suffering a venouseczema, often next to an existing VLU. The working mechanism of MMRC involves a combination of the moisturizingeffect of Aloe Vera gel and the moderate occlusion effect of added fatty acids.
Method: In an open case series, 18 patients attending an outpatient wound clinic with moderate venous eczema(maximum TIS score<3) participated. MMRC was applied twice a day and its use was clinically assessed for 4consecutive weeks. Next to the registration of patient characteristics and capturing the clinical details of the skinlesions in weekly pictures, a VAS scale to assess the patients’ and caregivers’ experience with the treatment wasused.
Results: During the application of MMRC, the signs and symptoms of a dry, itchy, scaly, crusty and erythematousskin, fainted in all patients. The skin condition of most participating patients improved and there was also a visiblybetter skin hydration status in all patients. Relevant aspects such as ‘night rest’, ‘mood’ and ‘social participation’improved, except for 2 patients. The clinical skin condition of one of these deteriorated in a week, which was notrelated to the use of MMRC. No side effects to the use of MMRC were observed. The wound care experiencednurses assessed MMRC as effective and feasible.
Conclusion: This study shows that MMRC is effective, safe, and feasible in the treatment of venous eczema.Future Randomized Controlled Trials are necessary to compare the efficacy and feasibility of MMRC

Original languageEnglish
Article number1000395
JournalJournal of Gerontology & Geriatric Research
Issue number1
Publication statusPublished - Feb 2017

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