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Applicability Assessment of Technologies for Predictive and Prescriptive Analytics of Nephrology Big Data

  • Riste Stojanov*
  • , Milos Jovanovik
  • , Sasho Gramatikov
  • , Igor Mishkovski
  • , Eftim Zdravevski
  • , Darko Sasanski
  • , Zorica Karapancheva
  • , Goce Spasovski
  • , Ivona Vasileska
  • , Tome Eftimov
  • , Zhuojun Wu
  • , Joachim Jankowski
  • , Dimitar Trajanov
  • *Corresponding author for this work

Research output: Contribution to journal(Systematic) Review articlepeer-review

Abstract

The integration of big data into nephrology research will open new avenues for analyzing and understanding complex biological datasets, driving advances in personalized management of kidney diseases. This paper describes the multifaceted challenges and opportunities by incorporating big data in nephrology, emphasizing the importance of data standardization, advanced storage solutions, and advanced analytical methods. We discuss the role of data science workflows, including data collection, preprocessing, integration, and analysis, in facilitating comprehensive insights into disease mechanisms and patient outcomes. Furthermore, we highlight predictive and prescriptive analytics, as well as the application of large language models (LLMs) in improving clinical decision-making and enhancing the accuracy of disease predictions. The use of high-performance computing (HPC) is also examined, showcasing its role in processing large-scale datasets and accelerating machine learning algorithms. Through this exploration, we aim to provide a comprehensive overview of the current state and future directions of big data analytics in nephrology, with a focus on enhancing patient care and advancing medical research.
Original languageEnglish
Article numbere202400135
Number of pages16
JournalProteomics
Volume25
Issue number11-12
Early online date27 May 2025
DOIs
Publication statusPublished - Jun 2025

Keywords

  • big data analytics
  • data integration
  • data standardization
  • large language models
  • nephrology
  • CHRONIC KIDNEY-DISEASE
  • MODEL
  • PROGRESSION
  • ONTOLOGY

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