Antiangiogenic factors and maternal hemodynamics during intensive hemodialysis in pregnancy.

T. Cornelis, M.E.A. Spaanderman, C. Beerenhout, F.H. Perschel, S. Verlohren, C.G. Schalkwijk, F.M. van der Sande, J.P. Kooman, M. Hladunewich

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

We report on a 21-year-old pregnant patient with IgA nephropathy who was initiated on intensive hemodialysis (8 hours of hemodialysis 3 times a gestational age of 26 weeks on the basis of worsening kidney function in rapidly progressive fatigue and difficulties in metabolic control. the pregnancy, and while on intensive hemodialysis, 24-hour ambulatory pressure control was within the target, and results of weekly 24-hour of central hemodynamics and pulse wave velocity, and of serial levels of circulating (anti-)angiogenic factors were comparable to normal Estimated fetal growth evolved along the 50th percentile, and no was detected. After induction for a sudden, unexplained increase in pressure, she delivered a healthy boy of 2480 g at a gestational age of This case adds to the expanding literature that supports the use of hemodialysis in pregnant patients with end-stage renal disease and for the first time, the potential use of serial (anti-) angiogenic 24-hour measurements of blood pressure and hemodynamic indices in order facilitate monitoring of these complicated patients.
Original languageEnglish
Pages (from-to)639-643
JournalHemodialysis international
Volume17
Issue number4
DOIs
Publication statusPublished - 1 Jan 2013

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