Anti-Sm antibodies in the classification criteria of systemic lupus erythematosus

Joyce J B C van Beers; Marco W J Schreurs

doi:10.1016/j.jtauto.2022.100155

Anti-Sm antibodies in the classification criteria of systemic lupus erythematosus

Joyce J B C van Beers, Marco W J Schreurs

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Systemic lupus erythematosus is characterized by autoantibodies and immune complex deposition. Several autoantibodies against mainly nuclear autoantigens have been described. One of these nuclear autoantigens is the Smith antigen. In this review, we focus on the position of autoantibodies against the Smith antigen in the classification criteria, the characteristics of the antigen, the production of anti-Smith antibodies in SLE and we discuss the different test methods available, together with their pitfalls, to detect these autoantibodies.

Original language	English
Article number	100155
Journal	Journal of Translational Autoimmunity
Volume	5
DOIs	https://doi.org/10.1016/j.jtauto.2022.100155
Publication status	Published - 2022

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10.1016/j.jtauto.2022.100155

Cite this

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title = "Anti-Sm antibodies in the classification criteria of systemic lupus erythematosus",

abstract = "Systemic lupus erythematosus is characterized by autoantibodies and immune complex deposition. Several autoantibodies against mainly nuclear autoantigens have been described. One of these nuclear autoantigens is the Smith antigen. In this review, we focus on the position of autoantibodies against the Smith antigen in the classification criteria, the characteristics of the antigen, the production of anti-Smith antibodies in SLE and we discuss the different test methods available, together with their pitfalls, to detect these autoantibodies.",

author = "{van Beers}, {Joyce J B C} and Schreurs, {Marco W J}",

note = "{\textcopyright} 2022 The Authors.",

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AB - Systemic lupus erythematosus is characterized by autoantibodies and immune complex deposition. Several autoantibodies against mainly nuclear autoantigens have been described. One of these nuclear autoantigens is the Smith antigen. In this review, we focus on the position of autoantibodies against the Smith antigen in the classification criteria, the characteristics of the antigen, the production of anti-Smith antibodies in SLE and we discuss the different test methods available, together with their pitfalls, to detect these autoantibodies.

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DO - 10.1016/j.jtauto.2022.100155

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JO - Journal of Translational Autoimmunity

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