TY - JOUR
T1 - Anti-Sm antibodies in the classification criteria of systemic lupus erythematosus
AU - van Beers, Joyce J B C
AU - Schreurs, Marco W J
N1 - © 2022 The Authors.
PY - 2022
Y1 - 2022
N2 - Systemic lupus erythematosus is characterized by autoantibodies and immune complex deposition. Several autoantibodies against mainly nuclear autoantigens have been described. One of these nuclear autoantigens is the Smith antigen. In this review, we focus on the position of autoantibodies against the Smith antigen in the classification criteria, the characteristics of the antigen, the production of anti-Smith antibodies in SLE and we discuss the different test methods available, together with their pitfalls, to detect these autoantibodies.
AB - Systemic lupus erythematosus is characterized by autoantibodies and immune complex deposition. Several autoantibodies against mainly nuclear autoantigens have been described. One of these nuclear autoantigens is the Smith antigen. In this review, we focus on the position of autoantibodies against the Smith antigen in the classification criteria, the characteristics of the antigen, the production of anti-Smith antibodies in SLE and we discuss the different test methods available, together with their pitfalls, to detect these autoantibodies.
U2 - 10.1016/j.jtauto.2022.100155
DO - 10.1016/j.jtauto.2022.100155
M3 - Article
C2 - 35464346
VL - 5
JO - Journal of Translational Autoimmunity
JF - Journal of Translational Autoimmunity
SN - 2589-9090
M1 - 100155
ER -