Anti-decubitus bed mattress may interfere with cerebrovascular pressure reactivity measures due to induced ICP and ABP cyclic peaks

T. Jeanette*, Melisa Borg, Peter Smielewski, Marek Czosnyka, E. Beqiri, E. Ari, A. Marcel

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

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Severe traumatic brain injury (TBI) patients are monitored with continuous arterial blood pressure (ABP) and intracranial pressure (ICP). The pressure reactivity index (PRx) is a frequently used correlation coefficient between ABP and ICP to inform clinicians at the bedside about trends in global cerebrovascular pressure regulation status. We present an unexpected influence of cyclic anti-decubitus mattress inflations and deflations on invasive ICP, ABP and PRx calculations in our TBI patients. This might affect autoregulation guided management. In our database, 23% (9/39) of the patients show recurrent peaks in the monitoring signals. We hypothesize that these peaks are caused by (a combination) of hydrostatic change, local (cervical) compression and/or incorrect sensor zeroing due to positional changes induced by the anti-decubitus mattress. This warrants further investigation by the manufacturer and exploration of data filters.
Original languageEnglish
Pages (from-to)423-425
Number of pages3
JournalJournal of Clinical Monitoring and Computing
Issue number2
Publication statusPublished - 1 Apr 2021


  • anti-decubitus bed mattress
  • icp
  • prx
  • traumatic brain-injury
  • ICP
  • Prx
  • Anti-decubitus bed mattress

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