Antagonizing alpha 7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition

Nick P. van Goethem; Dean Paes; Daniela Puzzo; Ernesto Fedele; Claudia Rebosio; Walter Gulisano; Agostino Palmeri; Lawrence P. Wennogle; Youyi Peng; Daniel Bertrand; Jos Prickaerts

doi:10.1016/j.cellsig.2019.06.003

Antagonizing alpha 7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition

Nick P. van Goethem, Dean Paes, Daniela Puzzo, Ernesto Fedele, Claudia Rebosio, Walter Gulisano, Agostino Palmeri, Lawrence P. Wennogle, Youyi Peng, Daniel Bertrand, Jos Prickaerts^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	109338
Pages (from-to)	1-8
Number of pages	8
Journal	Cellular Signalling
Volume	62
DOIs	https://doi.org/10.1016/j.cellsig.2019.06.003
Publication status	Published - Oct 2019

Keywords

alpha 7 nicotinic acetylcholine receptors
Ligand-gated ion channel
Antagonist
Receptor activity
Long-term potentiation
Memory acquisition
LONG-TERM POTENTIATION
ACETYLCHOLINE-RECEPTORS
BINDING-SITES
OBJECT RECOGNITION
IMPROVES MEMORY
ION CHANNELS
ONE-TRIAL
MECHANISMS
AGONIST
SYSTEM

Access to Document

10.1016/j.cellsig.2019.06.003

Cite this

van Goethem, Nick P. ; Paes, Dean ; Puzzo, Daniela ; Fedele, Ernesto ; Rebosio, Claudia ; Gulisano, Walter ; Palmeri, Agostino ; Wennogle, Lawrence P. ; Peng, Youyi ; Bertrand, Daniel ; Prickaerts, Jos. / Antagonizing alpha 7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition. In: Cellular Signalling. 2019 ; Vol. 62. pp. 1-8.

@article{bacd403dcb684ddf81a3412337892bdf,

title = "Antagonizing alpha 7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition",

keywords = "alpha 7 nicotinic acetylcholine receptors, Ligand-gated ion channel, Antagonist, Receptor activity, Long-term potentiation, Memory acquisition, LONG-TERM POTENTIATION, ACETYLCHOLINE-RECEPTORS, BINDING-SITES, OBJECT RECOGNITION, IMPROVES MEMORY, ION CHANNELS, ONE-TRIAL, MECHANISMS, AGONIST, SYSTEM",

author = "{van Goethem}, {Nick P.} and Dean Paes and Daniela Puzzo and Ernesto Fedele and Claudia Rebosio and Walter Gulisano and Agostino Palmeri and Wennogle, {Lawrence P.} and Youyi Peng and Daniel Bertrand and Jos Prickaerts",

year = "2019",

month = oct,

doi = "10.1016/j.cellsig.2019.06.003",

language = "English",

volume = "62",

pages = "1--8",

journal = "Cellular Signalling",

issn = "0898-6568",

publisher = "Elsevier Science",

}

Antagonizing alpha 7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition. / van Goethem, Nick P.; Paes, Dean; Puzzo, Daniela; Fedele, Ernesto; Rebosio, Claudia; Gulisano, Walter; Palmeri, Agostino; Wennogle, Lawrence P.; Peng, Youyi; Bertrand, Daniel; Prickaerts, Jos.

In: Cellular Signalling, Vol. 62, 109338, 10.2019, p. 1-8.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Antagonizing alpha 7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition

AU - van Goethem, Nick P.

AU - Paes, Dean

AU - Puzzo, Daniela

AU - Fedele, Ernesto

AU - Rebosio, Claudia

AU - Gulisano, Walter

AU - Palmeri, Agostino

AU - Wennogle, Lawrence P.

AU - Peng, Youyi

AU - Bertrand, Daniel

AU - Prickaerts, Jos

PY - 2019/10

Y1 - 2019/10

KW - alpha 7 nicotinic acetylcholine receptors

KW - Ligand-gated ion channel

KW - Antagonist

KW - Receptor activity

KW - Long-term potentiation

KW - Memory acquisition

KW - LONG-TERM POTENTIATION

KW - ACETYLCHOLINE-RECEPTORS

KW - BINDING-SITES

KW - OBJECT RECOGNITION

KW - IMPROVES MEMORY

KW - ION CHANNELS

KW - ONE-TRIAL

KW - MECHANISMS

KW - AGONIST

KW - SYSTEM

U2 - 10.1016/j.cellsig.2019.06.003

DO - 10.1016/j.cellsig.2019.06.003

M3 - Article

C2 - 31176021

VL - 62

SP - 1

EP - 8

JO - Cellular Signalling

JF - Cellular Signalling

SN - 0898-6568

M1 - 109338

ER -