Animal models of major depressive disorder and the implications for drug discovery and development

Konstantin A. Demin, Maxim Sysoev, Maria V. Chernysh, Anna K. Savva, Mamiko Koshiba, Edina A. Wappler-Guzzetta, Cai Song, Murilo S. De Abreu, Brian Leonard, Matthew O. Parker, Brian H. Harvey, Li Tian, Eero Vasar, Tatyana Strekalova, Tamara G. Amstislavskaya, Andrey D. Volgin, Erik T. Alpyshov, Dongmei Wang, Allan V. Kalueff*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Original languageEnglish
Pages (from-to)365-378
Number of pages14
JournalExpert Opinion on Drug Discovery
Volume14
Issue number4
DOIs
Publication statusPublished - 3 Apr 2019

Keywords

  • Depression
  • major depressive disorder
  • animal modeling
  • pathogenesis
  • endophenotype
  • GROOMING ANALYSIS ALGORITHM
  • PRIMATE SOCIAL-BEHAVIOR
  • BIOGENIC-AMINE ACTIVITY
  • SENSITIVE LINE RATS
  • MICE LACKING
  • INTERFERON-ALPHA
  • MOUSE MODEL
  • NEUROPSYCHIATRIC DISORDERS
  • ENVIRONMENTAL ENRICHMENT
  • OLFACTORY BULBECTOMY

Cite this

Demin, K. A., Sysoev, M., Chernysh, M. V., Savva, A. K., Koshiba, M., Wappler-Guzzetta, E. A., Song, C., De Abreu, M. S., Leonard, B., Parker, M. O., Harvey, B. H., Tian, L., Vasar, E., Strekalova, T., Amstislavskaya, T. G., Volgin, A. D., Alpyshov, E. T., Wang, D., & Kalueff, A. V. (2019). Animal models of major depressive disorder and the implications for drug discovery and development. Expert Opinion on Drug Discovery, 14(4), 365-378. https://doi.org/10.1080/17460441.2019.1575360