Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage

Angela Schulz; Nicola Victoria Mueller; Nina Anne van de Lest; Andreas Eisenreich; Martina Schmidbauer; Andrei Barysenka; Bettina Purfuerst; Anje Sporbert; Theodor Lorenzen; Alexander M. Meyer; Laura Herlan; Anika Witten; Frank Ruehle; Weibin Zhou; Emile de Heer; Marion Scharpfenecker; Daniela Panakova; Monika Stoll; Reinhold Kreutz

doi:10.7554/eLife.42068

Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage

Angela Schulz, Nicola Victoria Mueller, Nina Anne van de Lest, Andreas Eisenreich, Martina Schmidbauer, Andrei Barysenka, Bettina Purfuerst, Anje Sporbert, Theodor Lorenzen, Alexander M. Meyer, Laura Herlan, Anika Witten, Frank Ruehle, Weibin Zhou, Emile de Heer, Marion Scharpfenecker, Daniela Panakova^*, Monika Stoll, Reinhold Kreutz^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	42068
Number of pages	33
Journal	Elife
Volume	8
DOIs	https://doi.org/10.7554/eLife.42068
Publication status	Published - 22 Mar 2019

Keywords

WIDE ASSOCIATION
MWF RAT
ALBUMINURIA
PROTEINURIA
PODOCYTES
NEPHRIN
CHANNELS
REPLACEMENT
MUTAGENESIS
EXPRESSION

Access to Document

10.7554/eLife.42068

Cite this

Schulz, A., Mueller, N. V., van de Lest, N. A., Eisenreich, A., Schmidbauer, M., Barysenka, A., Purfuerst, B., Sporbert, A., Lorenzen, T., Meyer, A. M., Herlan, L., Witten, A., Ruehle, F., Zhou, W., de Heer, E., Scharpfenecker, M., Panakova, D., Stoll, M., & Kreutz, R. (2019). Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage. Elife, 8, [42068]. https://doi.org/10.7554/eLife.42068

Schulz, Angela ; Mueller, Nicola Victoria ; van de Lest, Nina Anne ; Eisenreich, Andreas ; Schmidbauer, Martina ; Barysenka, Andrei ; Purfuerst, Bettina ; Sporbert, Anje ; Lorenzen, Theodor ; Meyer, Alexander M. ; Herlan, Laura ; Witten, Anika ; Ruehle, Frank ; Zhou, Weibin ; de Heer, Emile ; Scharpfenecker, Marion ; Panakova, Daniela ; Stoll, Monika ; Kreutz, Reinhold. / Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage. In: Elife. 2019 ; Vol. 8.

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title = "Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage",

keywords = "WIDE ASSOCIATION, MWF RAT, ALBUMINURIA, PROTEINURIA, PODOCYTES, NEPHRIN, CHANNELS, REPLACEMENT, MUTAGENESIS, EXPRESSION",

author = "Angela Schulz and Mueller, {Nicola Victoria} and {van de Lest}, {Nina Anne} and Andreas Eisenreich and Martina Schmidbauer and Andrei Barysenka and Bettina Purfuerst and Anje Sporbert and Theodor Lorenzen and Meyer, {Alexander M.} and Laura Herlan and Anika Witten and Frank Ruehle and Weibin Zhou and {de Heer}, Emile and Marion Scharpfenecker and Daniela Panakova and Monika Stoll and Reinhold Kreutz",

year = "2019",

month = mar,

day = "22",

doi = "10.7554/eLife.42068",

language = "English",

volume = "8",

journal = "Elife",

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Schulz, A, Mueller, NV, van de Lest, NA, Eisenreich, A, Schmidbauer, M, Barysenka, A, Purfuerst, B, Sporbert, A, Lorenzen, T, Meyer, AM, Herlan, L, Witten, A, Ruehle, F, Zhou, W, de Heer, E, Scharpfenecker, M, Panakova, D, Stoll, M & Kreutz, R 2019, 'Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage', Elife, vol. 8, 42068. https://doi.org/10.7554/eLife.42068

Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage. / Schulz, Angela; Mueller, Nicola Victoria; van de Lest, Nina Anne; Eisenreich, Andreas; Schmidbauer, Martina; Barysenka, Andrei; Purfuerst, Bettina; Sporbert, Anje; Lorenzen, Theodor; Meyer, Alexander M.; Herlan, Laura; Witten, Anika; Ruehle, Frank; Zhou, Weibin; de Heer, Emile; Scharpfenecker, Marion; Panakova, Daniela; Stoll, Monika; Kreutz, Reinhold.

In: Elife, Vol. 8, 42068, 22.03.2019.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage

AU - Schulz, Angela

AU - Mueller, Nicola Victoria

AU - van de Lest, Nina Anne

AU - Eisenreich, Andreas

AU - Schmidbauer, Martina

AU - Barysenka, Andrei

AU - Purfuerst, Bettina

AU - Sporbert, Anje

AU - Lorenzen, Theodor

AU - Meyer, Alexander M.

AU - Herlan, Laura

AU - Witten, Anika

AU - Ruehle, Frank

AU - Zhou, Weibin

AU - de Heer, Emile

AU - Scharpfenecker, Marion

AU - Panakova, Daniela

AU - Stoll, Monika

AU - Kreutz, Reinhold

PY - 2019/3/22

Y1 - 2019/3/22

KW - WIDE ASSOCIATION

KW - MWF RAT

KW - ALBUMINURIA

KW - PROTEINURIA

KW - PODOCYTES

KW - NEPHRIN

KW - CHANNELS

KW - REPLACEMENT

KW - MUTAGENESIS

KW - EXPRESSION

U2 - 10.7554/eLife.42068

DO - 10.7554/eLife.42068

M3 - Article

C2 - 30900988

VL - 8

JO - Elife

JF - Elife

SN - 2050-084X

M1 - 42068

ER -