Abstract
Hypermobility spectrum disorders (HSD) and hypermobility Ehlers-Danlos syndrome (hEDS) are frequently associated with gastrointestinal symptoms, although the underlying mechanisms remain unclear. This study aimed to compare antroduodenal motility in patients with and without HSD/hEDS. We included 239 patients (50 HSD/hEDS and 189 non-HSD/hEDS) with gastrointestinal symptoms undergoing antroduodenal manometry (ADM). The prevalence of antroduodenal dysmotility was not different between both groups, but enteric dysmotility was less common in the HSD/hEDS group (13% vs. 34%, p = 0.006). Delayed gastric emptying rates were similar, suggesting that delayed gastric emptying is more relevant for patients with HSD/hEDS and gastrointestinal symptoms.
Original language | English |
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Article number | 18471 |
Pages (from-to) | 702-705 |
Number of pages | 4 |
Journal | Alimentary Pharmacology & Therapeutics |
Volume | 61 |
Issue number | 4 |
DOIs | |
Publication status | Published - Feb 2025 |
Keywords
- gastric emptying
- motility
- stomach and duodenum
- DISORDERS