An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene

Janou A. Y. Roubroeks, Adam R. Smith, Rebecca G. Smith, Ehsan Pishva, Zina Ibrahim, Martina Sattlecker, Eilis J. Hannon, Iwona Kloszewska, Patrizia Mecocci, Hilkka Soininen, Magda Tsolaki, Bruno Vellas, Lars-Olof Wahlund, Dag Aarsland, Petroula Proitsi, Angela Hodges, Simon Lovestone, Stephen J. Newhouse, Richard J. B. Dobson, Jonathan MillDaniel L. A. van den Hove, Katie Lunnon*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)26-45
Number of pages20
JournalNeurobiology of Aging
Volume95
DOIs
Publication statusPublished - Nov 2020

Keywords

  • Alzheimer's disease (AD)
  • Biomarker
  • Blood
  • DNA methylation
  • HOXB6
  • Mild cognitive impairment (MCI)
  • MILD COGNITIVE IMPAIRMENT
  • MESSENGER-RNA EXPRESSION
  • METHYLATION
  • BIOMARKERS
  • OXYTOCIN
  • DISCOVERY
  • ALGORITHM
  • DEMENTIA
  • PATTERN
  • PACKAGE

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